Academic Journal
Studying the Interaction of Viteral Substitutes with the Surface of Acrylic Intraocular Lenses ; Изучение взаимодействия заместителей стекловидного тела с поверхностью акриловых интраокулярных линз
| العنوان: | Studying the Interaction of Viteral Substitutes with the Surface of Acrylic Intraocular Lenses ; Изучение взаимодействия заместителей стекловидного тела с поверхностью акриловых интраокулярных линз |
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| المؤلفون: | M. A. Plakhotniy, A. G. Shichkova, O. S. Kuznetsova, A. V. Tereschenko, I. G. Trifanenkova, N. N. Yudina, N. M. Shilov, М. А. Плахотний, А. Г. Шичкова, О. С. Кузнецова, А. В. Терещенко, И. Г. Трифаненкова, Н. Н. Юдина, Н. М. Шилов |
| المصدر: | Ophthalmology in Russia; Том 20, № 4 (2023); 688-695 ; Офтальмология; Том 20, № 4 (2023); 688-695 ; 2500-0845 ; 1816-5095 ; 10.18008/1816-5095-2023-4 |
| بيانات النشر: | Ophthalmology |
| سنة النشر: | 2023 |
| المجموعة: | Ophthalmology (E-Journal) / Офтальмология |
| مصطلحات موضوعية: | адгезия, hydrophobic acrylic polymer, silicone oil, perfluorodecalin, adhesion, гидрофобный акриловый полимер, силиконовое масло, перфтордекалин |
| الوصف: | Purpose of the study: In vitro to study the degree of adhesion of vitreous substitutes, such as silicone oil of various viscosities and perfluorodecalin (PFOS), to hydrophobic acrylic polymer IOLs and evaluate the interaction of vitreous substitutes with the model MIOL-Soft-23 in the clinic. Material and methods. IOLs of the model MIOL-Soft-23 were taken for the experiment. MIOL-Soft-23 are included in the RPR-20 set. IOL of the model MIOL-Soft-23 is made by photopolymerization from a biocompatible spatially cross-linked hydrophobic acrylic polymer based on oligomers and monomers of the methacrylic series with filters in the ultraviolet region of the spectrum from 19 to 23 D. For the experiment, silicone oils of different viscosities were taken: RS-OIL 2000 (Alchimia), SIL-5000-S (DORC), Oxane 5700 (Bausch & Lomb), PFOS (perfluorodecalin) Dk-line (Bausch & Lomb). Also, saline sodium chloride 0.9 % (Solofarm) was used. Results. Revealed a decrease in the degree of silicone adhesion to the surface of acrylic hydrophobic IOLs as the temperature rises, not less than 1.5 %. The absence of dependence of the degree of adhesion on the degree of viscosity of silicone oil was confirmed, which corresponds to the literature data. For the first time, the average percentage of adhesion of perfluorodecalin to the IOL surface data were obtained, in particular, the MIOL-Soft-23 model. The range of values ranged from 0.7 to 7.2 %. The average coverage percentage is 1.9 ± 1.3 % (exposure at 37 ± 1 °C for up to 14 days) and 3.4 ± 1.5 % (exposure at room temperature for up to 14 days). This confirms the need for careful intraoperative monitoring of the completeness of removal of PFOS droplets from the IOL surface. Conclusion. The presence of the risk of adhesion of residual drops of silicone oil and PFOS to the surface of the IOL necessitates careful intraoperative control of the completeness of the removal of vitreous body substitutes, as well as further search for the best ways to eliminate this complication. The conducted ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Russian |
| Relation: | https://www.ophthalmojournal.com/opht/article/view/2238/1164; Apple DJ, Federman JL, Krolicki TJ, Sims JC, Kent DG, Hamburger HA, Smiddy WE, Cox Jr MS, Hassan TS, Compton SM, Thomas SG. Irreversible silicone oil adhesion to silicone intraocular lenses. A clinicopathologic analysis. Ophthalmology. 1996;103(10):1555–1562.doi:10.1016/s0161-6420(96)30463-6.; McLoone E, Mahon G, Archer D, Best R. Silicone oil-intraocular lens interaction: which lens touse? Br J Ophthalmol. 2001;85:543–545. doi:10.1136/bjo.85.5.543.; Kusaka S, Kodama T, Ohashi Y. Condensation of silicone oil on the posterior surface of a silicone intraocular lens during vitrectomy. American Journal of Ophthalmology. 1996;121(5):574–575. doi:10.1016/s0002-9394(14)75436-4.; Arthur SN, Peng Q, Apple DJ, Escobar-Gomez M, Bianchi R, Pandey SK, Werner L. Effect of heparin surface modification in reducing silicone oil adherence to various intraocular lenses. Journal of Cataract & Refractive Surgery. 2001;27(10):1662–1669. doi:10.1016/s0886-3350(01)00891-4.; Apple DJ, Isaacs RT, Kent DG, Martinez LM, Kim S, Thomas SG, Basti S, Barker D, Peng Q. Silicone oil adhesion to intraocular lenses: An experimental study comparing various biomaterials. J Cataract Refract Surg. 1997;23(4):536-44: doi:10.1016/s0886-3350(97)80210-6.; Rosca C, Munteanu M, Tamasoi I, Petrovic Z, Balica N, Nicula C, Cretu O. Calcification of hydrophilic acrylic intraocular lens in eyes with silicone oil tamponade — an interventional case series report. Acta Ophthalmologica. 2016;94(6):625–627. doi:10.1111/aos.12887.; Huang XD, Li HY, Lin L, Yao K. Reduced silicone oil adherence to silicone intraocular lens by surface modification with 2-methacryloyloxyethyl phosphoryl-choline. Current Eye Research. 2013;38(1):91–96. doi:10.3109/02713683.2012.704477.; Öner HF, Saatci OA, Sarioglub S, Durak I, Kaynak S, Çabuk M. Interaction of Intraocular Lenses with Various Concentrations of Silicone Oil: An Experimental Study. Ophthalmologica. 2003;217:124–128. doi:10.1159/000068561.; Auffarth GU, Fang H, Wang Q, Hengerer F, Khoramnia R, Son HS, Schickhardt S. Silicone Oil Adhesion to Hydrophobic Acrylic Intraocular Lenses: A Comparative Laboratory Study of a New versus an Established Hydrophobic Acrylic IntraocularLensMaterial. Journal of Ophthalmology. 2021;10:1387987. doi:10.1155/2021/1387987.; Mertens S, Bednarz J, Engelmann K. Evidence of toxic side effects of perfluorohexyloctane after vitreoretinal surgery as well as in previously established in vitro models with ocular cell types. Graefes Arch Clin Exp Ophthalmol. 2002;240(12):989–995. doi:10.1007/s00417-002-0561-0.; Schulz A, Szurman P. Vitreous Substitutes as Drug Release Systems. Transl Vis Sci Technol. 2022;11(9):14. doi:10.1167/tvst.11.9.14.; https://www.ophthalmojournal.com/opht/article/view/2238 |
| DOI: | 10.18008/1816-5095-2023-4-688-695 |
| الاتاحة: | https://www.ophthalmojournal.com/opht/article/view/2238 https://doi.org/10.18008/1816-5095-2023-4-688-695 |
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| رقم الانضمام: | edsbas.829C3FC8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.18008/1816-5095-2023-4-688-695 |
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