Academic Journal
Inflammatory response to different endodontic irrigating solutions
| العنوان: | Inflammatory response to different endodontic irrigating solutions |
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| المؤلفون: | Tanomaru, M., Leonardo, M. R., Silva, LAB, Anibal, F. F., Faccioli, L. H. |
| المساهمون: | Universidade Estadual Paulista (UNESP) |
| بيانات النشر: | Blackwell Publishing |
| سنة النشر: | 2002 |
| المجموعة: | Universidade Estadual Paulista São Paulo: Repositório Institucional UNESP |
| مصطلحات موضوعية: | biocompatibility, chlorhexidine, endodontic irrigating solutions, inflammation |
| الوصف: | Aim the aim of this study was to evaluate the inflammatory response to irrigating solutions injected into the peritoneal cavity of mice.Methodology Sixty mice received intra-peritoneal injections of 0.3 mL of 0.5% sodium hypochlorite, 2.0% chlorhexidine digluconate or phosphate buffered saline (PBS, control). Five animals of each group were sacrificed at 4, 24, 48 h and 7 days after the injection. Liquid from the peritoneal cavity of each animal was collected for the total and differential counting of inflammatory cells and protein leakage.Results the 0.5% sodium hypochlorite solution group had greater migration of neutrophils and mononuclear cells to the peritoneal cavity from 48 to 168 h (P < 0.05). There was a significant increase in protein leakage to the peritoneal cavity after 4 up to 48 h in the 0.5% sodium hypochlorite group compared to the control group. Protein leakage was similar in all groups at 168 h. The 2.0% chlorhexidine group had similar results to the control group at all time periods.Conclusions the 0.5% sodium hypochlorite solution induced an inflammatory response, however, the 2.0% chlorhexidine digluconate solution did not induce a significant inflammatory response. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | 735-739 |
| اللغة: | English |
| تدمد: | 0143-2885 |
| Relation: | International Endodontic Journal; 3.015; 1,791; http://dx.doi.org/10.1046/j.1365-2591.2002.00544.x; International Endodontic Journal. Oxford: Blackwell Publishing Ltd, v. 35, n. 9, p. 735-739, 2002.; http://hdl.handle.net/11449/34815; WOS:000177789800002 |
| DOI: | 10.1046/j.1365-2591.2002.00544.x |
| الاتاحة: | http://hdl.handle.net/11449/34815 https://doi.org/10.1046/j.1365-2591.2002.00544.x |
| Rights: | closedAccess |
| رقم الانضمام: | edsbas.829AF324 |
| قاعدة البيانات: | BASE |
| تدمد: | 01432885 |
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| DOI: | 10.1046/j.1365-2591.2002.00544.x |