Academic Journal
Comparison of neonatal outcomes between multiples and singletons among very low birth weight infants: the Korean Neonatal Network cohort study
| العنوان: | Comparison of neonatal outcomes between multiples and singletons among very low birth weight infants: the Korean Neonatal Network cohort study |
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| المؤلفون: | Jang, HG, Choi, S, Noh, OK, Hwang, JH, Lee, JH, Korean Neonatal Network |
| المساهمون: | 114996, 107599, 107982, Choi, S, Noh, OK, Lee, JH |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Birth Weight, Cesarean Section, Cohort Studies, Female, Gestational Age, Hemorrhage, Humans, Infant, Infant Mortality, Newborn, Very Low Birth Weight, Pregnancy, Multiple, Prospective Studies, Republic of Korea, Retinopathy of Prematurity, Retrospective Studies, outcome |
| الوصف: | Objective: To compare neonatal outcomes between multiples and singletons among very low birth weight infants, this was a prospective cohort study that was conducted by collecting data registered in the Korean Neonatal Network database. Methods: From January 2013 to December 2016, there were 8265 infants in the Korean Neonatal Network database, and 2958 of them were from multiples. Among them, 2636 infants were twins, 308 infants were triplets, and 14 infants were quadruplets. Maternal and neonatal variables including and mortality major morbidity were compared. Finally, the predicted rates of major morbidity between singletons and multiples. Results: Multiples had higher gestational age, birth weight, Apgar score at 5 min, rates of cesarean section and artificial reproductive technology but lower maternal hypertension, oligohydramnios, chorioamnionitis rates and Clinical Risk Index for Babies scores II without base excess than the singletons. In univariate analysis, multiples had a lower incidence of respiratory distress syndrome, bronchopulmonary dysplasia, and sepsis. The mortality rate was not significantly different for overall gestational ages except for those born at ≤26 weeks of gestation. In multivariate logistic analysis, the incidences of intraventricular hemorrhage (grade ≥3), and retinopathy of prematurity requiring treatment were significantly higher than the singletons. Conclusions: Mortality was not significantly different between multiples and singletons according to overall gestational age, except for multiples born at ≤26 weeks. A significant higher risk of intraventricular hemorrhage and retinopathy of prematurity requiring treatment was found in multiples. A new strategy to improve the mortality of immature multiples born at ≤26 weeks of gestation should be developed. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1476-7058 1476-4954 |
| Relation: | J014767058; http://repository.ajou.ac.kr/handle/201003/26348; The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 36(2). : 2245530-2245530, 2023 |
| DOI: | 10.1080/14767058.2023.2245530 |
| الاتاحة: | http://repository.ajou.ac.kr/handle/201003/26348 https://www.tandfonline.com/doi/full/10.1080/14767058.2023.2245530 https://doi.org/10.1080/14767058.2023.2245530 |
| رقم الانضمام: | edsbas.8296C247 |
| قاعدة البيانات: | BASE |
| تدمد: | 14767058 14764954 |
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| DOI: | 10.1080/14767058.2023.2245530 |