Academic Journal
A Short-Term Enteral Nutrition Protocol for Management of Adult Crohn’s Disease—A Pilot Trial
العنوان: | A Short-Term Enteral Nutrition Protocol for Management of Adult Crohn’s Disease—A Pilot Trial |
---|---|
المؤلفون: | Levi Teigen, Matthew Hamilton, Austin Hoeg, Lulu Chen, Sharon Lopez, Amanda Kabage, Priyali Shah, Eugenia Shmidt, Byron Vaughn |
المصدر: | Journal of Clinical Medicine, Vol 13, Iss 6, p 1663 (2024) |
بيانات النشر: | MDPI AG |
سنة النشر: | 2024 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | Crohn’s disease, partial enteral nutrition, diet, microbiome, Medicine |
الوصف: | Crohn’s disease (CD) is often treated with either exclusive or supplemental enteral nutrition (EN) in pediatrics, but adult practice guidelines primarily focus on medications. Here, we demonstrate the feasibility of a 4-week semi-elemental-formula-based oral nutrition delivery program for managing adult CD ( n = 4). Patients consumed ~66% of calories from the formula, a finding that might provide an improved calorie target for future trials. We identified Flavinofractor as the only differentially abundant genus, distinguishing post-intervention samples from pre-intervention samples. Findings from this pilot trial demonstrate the feasibility of a partial enteral nutrition protocol in adult CD management and contribute to the growing body of literature on the potential role of EN therapy in adults with CD. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2077-0383 |
Relation: | https://www.mdpi.com/2077-0383/13/6/1663; https://doaj.org/toc/2077-0383; https://doaj.org/article/2fa8cafbd4994205ace6676c50cb596e |
DOI: | 10.3390/jcm13061663 |
الاتاحة: | https://doi.org/10.3390/jcm13061663 https://doaj.org/article/2fa8cafbd4994205ace6676c50cb596e |
رقم الانضمام: | edsbas.828727B2 |
قاعدة البيانات: | BASE |
تدمد: | 20770383 |
---|---|
DOI: | 10.3390/jcm13061663 |