Academic Journal
Oligonucleotide nanoassemblies with allyl bromide scaffold-based small molecules
| العنوان: | Oligonucleotide nanoassemblies with allyl bromide scaffold-based small molecules |
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| المؤلفون: | Abbas, Sk Jahir, Yesmin, Sabina, Xia, Fangfang, Ali, Sk Imran, Xiao, Zeyu, Tan, Weihong |
| المساهمون: | National Natural Science Foundation of China, National Key Research and Development Program of China |
| المصدر: | Discover Nano ; volume 18, issue 1 ; ISSN 2731-9229 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2023 |
| الوصف: | The development of oligonucleotide nanoassemblies with small molecules has shown great potential in bio-medical applications. However, the interaction of negatively charged oligonucleotides with halogenated small molecules represents a scientific challenge. Here, we introduced a distinct allyl bromide halogenated scaffold, which exhibits specific interaction with adenine nucleic bases of the oligonucleotides, thus leading to the formation of self-assembled nanostructures. Graphical abstract |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1186/s11671-023-03846-0 |
| DOI: | 10.1186/s11671-023-03846-0.pdf |
| DOI: | 10.1186/s11671-023-03846-0/fulltext.html |
| الاتاحة: | http://dx.doi.org/10.1186/s11671-023-03846-0 https://link.springer.com/content/pdf/10.1186/s11671-023-03846-0.pdf https://link.springer.com/article/10.1186/s11671-023-03846-0/fulltext.html |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.827977DF |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s11671-023-03846-0 |
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