Academic Journal

Reference intervals for mean platelet volume and immature platelet fraction determined on a sysmex XE5000 hematology analyzer

التفاصيل البيبلوغرافية
العنوان: Reference intervals for mean platelet volume and immature platelet fraction determined on a sysmex XE5000 hematology analyzer
المؤلفون: Jørgensen, Mikala Klok, Bathum, L.
المصدر: Jørgensen , M K & Bathum , L 2016 , ' Reference intervals for mean platelet volume and immature platelet fraction determined on a sysmex XE5000 hematology analyzer ' , Scandinavian Journal of Clinical & Laboratory Investigation , vol. 76 , no. 2 , pp. 172-176 . https://doi.org/10.3109/00365513.2015.1124448
سنة النشر: 2016
المجموعة: University of Southern Denmark: Research Output / Syddansk Universitet
مصطلحات موضوعية: European Continental Ancestry Group, Reference values, hematology, mean platelet volume, normal range, platelet count, thrombopoiesis, Age Distribution, Humans, Middle Aged, Male, Hematology/instrumentation, Smoking/blood, Sex Distribution, Adult, Female, Aged, Mean Platelet Volume/instrumentation
الوصف: Background New parameters describing the platelet population of the blood are mean platelet volume (MPV), which is a crude estimate of thrombocyte reactivity, and immature platelet fraction (IPF), which reflects megakaryopoietic activity. This study aimed to define reference intervals for MPV and IPF and to investigate whether separate reference intervals according to smoking status, age or sex are necessary.Methods Blood samples were obtained from subjects participating in The Danish General Suburban Population Study. MPV and IPF measurements were performed by the use of the Sysmex XE-5000 hematology analyzer. Reference intervals were established by a non-parametric method.Results In total, 1674 apparently healthy individuals (910 females and 764 males) were included. No significant age, sex or smoking status difference was observed. The reference interval was 9.6-13.1 fL for MPV and 1.3-9.0% for IPF, respectively.Conclusion We have generated reference intervals for MPV and IPF in a large, adult Danish population and found those parameters remarkably stable across age, sex and smoking status.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: https://portal.findresearcher.sdu.dk/da/publications/f6e38244-ec38-4662-96e3-5163342a78b8
DOI: 10.3109/00365513.2015.1124448
الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/f6e38244-ec38-4662-96e3-5163342a78b8
https://doi.org/10.3109/00365513.2015.1124448
Rights: info:eu-repo/semantics/closedAccess
رقم الانضمام: edsbas.824D3E2E
قاعدة البيانات: BASE
الوصف
DOI:10.3109/00365513.2015.1124448