The trajectory and characteristics of mononuclear phagocytes’ differentiation into macrophages.

التفاصيل البيبلوغرافية
العنوان: The trajectory and characteristics of mononuclear phagocytes’ differentiation into macrophages.
المؤلفون: Tiantian Ji, Haoyu Fu, Liping Wang, Jinyun Chen, Shaobo Tian, Guobin Wang, Lin Wang, Zheng Wang
سنة النشر: 2024
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Biotechnology, Immunology, Developmental Biology, Cancer, Biological Sciences not elsewhere classified, potential therapeutic targets, main immune cells, current studies show, cell rna sequencing, 6 different subsets, mononuclear phagocytes comprehensively, inflammatory mononuclear phagocytes, classify mononuclear phagocytes, circulating monocytes differentiation, new subset associated, mononuclear phagocytes, transcription factor, tissue inhibitor, terminal state, remarkable plasticity, negatively correlated, major cause, lipid metabolism, immunological function, findings advance
الوصف: (A). Pseudotime plot showed the dynamics of mononuclear phagocytes. (B). Pseudotime plot of mononuclear phagocytes showed stages of each cluster. (C). Developmental trajectory of mononuclear phagocytes inferred by RNA velocity. Arrows indicate developmental trend of each cell. (D). Heatmap showed downregulated inflammatory genes and upregulated immunosuppression-related genes in the differentiation of mononuclear phagocytes.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/The_trajectory_and_characteristics_of_mononuclear_phagocytes_differentiation_into_macrophages_/25291927
DOI: 10.1371/journal.pgen.1011176.g004
الاتاحة: https://doi.org/10.1371/journal.pgen.1011176.g004
https://figshare.com/articles/figure/The_trajectory_and_characteristics_of_mononuclear_phagocytes_differentiation_into_macrophages_/25291927
Rights: CC BY 4.0
رقم الانضمام: edsbas.811AE6F1
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pgen.1011176.g004