Academic Journal
One-pot multiphosphinylation & -phosphonylation of pyridine and related heterocycles towards the synthesis of piperidinylphosphonates and -phosphine oxides
| العنوان: | One-pot multiphosphinylation & -phosphonylation of pyridine and related heterocycles towards the synthesis of piperidinylphosphonates and -phosphine oxides |
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| المؤلفون: | Simoens, Andreas, Pouranick, Prakhar, Bonneure, Eli, Sarazin, Johan, Drabowicz, Jozef, Assche, Guy Van, Stevens, Christian |
| المساهمون: | Koutentis, Panayiotis A. |
| المصدر: | ARKIVOC ; ISSN: 1551-7004 ; ISSN: 1551-7012 |
| سنة النشر: | 2024 |
| المجموعة: | Ghent University Academic Bibliography |
| مصطلحات موضوعية: | Chemistry, Phosphonylation, phosphinylation, pyridine, piperidine, flame retardants, phosphine oxides, phosphonates, FLAME-RETARDANT, DIPHOSPHONYLATION, COMPLEXES, CATALYSTS, CALCIUM |
| الوصف: | Herein a new protocol for the multiphosphinylation and-phosphonylation of pyridine and related heterocycles is described to give access to piperidinyl phosphine oxides and - phosphonates. The former are accessible through a straightforward, neat, one-pot reaction which yielded the desired phosphinylated heterocycles moderate to excellent yields (42-99%). These compounds contain a high phosphorus to carbon ratio and were evaluated using TGA and calorimetric measurements for potential flame-retardant applications. The respective phosphonates could be obtained using a second protocol, which employed pyridinium salts, triakly phosphites, formic acid and silica to promote the reaction. These piperidinyl phosphonates were isolated moderate to good yields (38-81%) and provide also an interesting starting point for potential enzyme inhibitors. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://biblio.ugent.be/publication/01JAT0P0J09JEQDJ267XPAA8V3; http://doi.org/10.24820/ark.5550190.p012.259; https://biblio.ugent.be/publication/01JAT0P0J09JEQDJ267XPAA8V3/file/01JCJRNNBSX8QHKWCJ76QKT560 |
| DOI: | 10.24820/ark.5550190.p012.259 |
| الاتاحة: | https://biblio.ugent.be/publication/01JAT0P0J09JEQDJ267XPAA8V3 http://hdl.handle.net/1854/LU-01JAT0P0J09JEQDJ267XPAA8V3 https://doi.org/10.24820/ark.5550190.p012.259 https://biblio.ugent.be/publication/01JAT0P0J09JEQDJ267XPAA8V3/file/01JCJRNNBSX8QHKWCJ76QKT560 |
| Rights: | Creative Commons Attribution 4.0 International Public License (CC-BY 4.0) ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.7F60D0FA |
| قاعدة البيانات: | BASE |
| DOI: | 10.24820/ark.5550190.p012.259 |
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