Academic Journal

Effect of long-term steroid withdrawal in renal transplant recipients: a retrospective cohort study

التفاصيل البيبلوغرافية
العنوان: Effect of long-term steroid withdrawal in renal transplant recipients: a retrospective cohort study
المؤلفون: Miguel Gonzalez-molina, Miguel Angel Gentil, Dolores Burgos, Mercedes Cabello, Carmen Cobelo, Jesús Bustamante, Pedro Errasti, Antonio Franco, Domingo Hernández
المساهمون: The Pennsylvania State University CiteSeerX Archives
المصدر: ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/0b/d1/NDT_Plus_2010_Jun_3(suppl_2)_ii32-ii36.tar.gz
المجموعة: CiteSeerX
الوصف: Background. Steroids are largely effective for the immunosuppressive treatment in renal transplant patients, but cause severe side effects. Whether steroid withdrawal confers long-term beneficial effects remains unclear. Methods. Data on 4481 cadaveric kidney transplant recipients were collected to estimate the impact of steroid withdrawal on kidney function and graft and patient survival using multivariate Cox regression models. Results. A total of 923 patients (20.6%) had steroid treatment withdrawn. This was more common in recipients from younger donors and in older recipients, and in recipients with a first transplant, those who had pre-transplant or de novo diabetes mellitus and those with fewer episodes of acute rejection (AR) (22.4 % vs. 29.2%, P < 0.001). Cox multivariate
نوع الوثيقة: text
وصف الملف: application/zip
اللغة: English
Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.1334
الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.354.1334
Rights: Metadata may be used without restrictions as long as the oai identifier remains attached to it.
رقم الانضمام: edsbas.7ED8CC52
قاعدة البيانات: BASE