Academic Journal

Preparation of Vitamin-g-Lignin Nanohybrids with Excellent Biological Activity and Fluorescence Performance

التفاصيل البيبلوغرافية
العنوان: Preparation of Vitamin-g-Lignin Nanohybrids with Excellent Biological Activity and Fluorescence Performance
المؤلفون: Yang, Weijun, Zhang, Xujing, Zhang, Ying, Gao, Daqian, Puglia, Debora, Xu, Pengwu, Ma, Piming
المساهمون: Yang, Weijun, Zhang, Xujing, Zhang, Ying, Gao, Daqian, Puglia, Debora, Xu, Pengwu, Ma, Piming
سنة النشر: 2024
المجموعة: IRIS Università degli Studi di Perugia
الوصف: As a natural renewable biomacromolecule, lignin has some inherently interesting properties such as fluorescence, antioxidation, and antibacterial performance. However, the unsatisfactory fluorescence and biological activities have greatly limited their value-added and large-scale applications. In this work, lignin nanoparticles (LNPs) grafted with vitamin B-1 hybrid nanoparticles (LEVs) were obtained by using ethylenediamine and different contents of vitamin B-1 through a simple hydrothermal method. The chemical structure, fluorescence properties, and bioactivity were characterized to assess the effects of ethylenediamine and vitamin B-1 on the properties of LEVs. It was found that the fluorescence performance of synthesized LEV particles was improved with the increase in the amount of vitamin B-1. The free radical scavenging rate (RSA, %) increased to 97.8%, while the antibacterial rates reached up to 99.9%. The antibacterial activity of LEV involved multiple combined mechanisms. The introduction of imine, amide groups, and positively charged VB1 of LEV will make it easier to interact with the negatively charged bacterial phospholipid membranes and cause bacterial lysis and death. Then, the PVA/LEV hydrogel composites were prepared by the freezing-thawing method, and the results showed that PVA/LEV hydrogels had more comprehensive performance such as improved mechanical properties and antioxidant and antibacterial activities, resulting in its great potential to be used as an efficient biomedical material.
نوع الوثيقة: article in journal/newspaper
وصف الملف: ELETTRONICO
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/38922332; info:eu-repo/semantics/altIdentifier/wos/WOS:001255957100001; volume:25; issue:7; firstpage:4604; lastpage:4614; numberofpages:11; journal:BIOMACROMOLECULES; https://hdl.handle.net/11391/1577694; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85196977006
DOI: 10.1021/acs.biomac.4c00681
الاتاحة: https://hdl.handle.net/11391/1577694
https://doi.org/10.1021/acs.biomac.4c00681
رقم الانضمام: edsbas.7EA23469
قاعدة البيانات: BASE
الوصف
DOI:10.1021/acs.biomac.4c00681