Academic Journal
A Nationwide Survey of Lymphangioleiomyomatosis in Korea: Recent Increase in Newly Diagnosed Patients
| العنوان: | A Nationwide Survey of Lymphangioleiomyomatosis in Korea: Recent Increase in Newly Diagnosed Patients |
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| المؤلفون: | Park, Hye Yun, Nam, Hae-Seong, Chung, Man Pyo, Jeong, Sung Hwan, Cha, Seung-Ick, Park, Jong Sun, Park, Choon-Sik, Moon, Ji Ae, Jegal, Yang Jin, Park, Young Bum, Yum, Ho-Kee, Song, Jin Woo, Kim, Dong Soon, Jung, Kyung Soo, Park, Moo Suk, Uh, Soo-Taek, Kim, Young Whan, Kim, Yu Jin |
| المساهمون: | 박혜윤, 남해성, 정만표, 정성환, 김유진, 차승익, 김영환, 박종선, 어수택, 박준식, 박무석, 문지애, 정경수, 제갈양진, 김동순, 송진우, 염호기, 박용범 |
| بيانات النشر: | KOREAN ACAD MEDICAL SCIENCES |
| سنة النشر: | 2010 |
| المجموعة: | Seoul National University: S-Space |
| مصطلحات موضوعية: | Lymphangioleiomyomatosis, Respiratory Function Tests, Registries, Korea |
| الوصف: | In 2007, the Korean Interstitial Lung Disease Society had collected clinical data of patients who have diagnosed as Lymphangioleiomyomatosis (LAM) since 1990 through nationwide survey, which showed that LAM patients had increased sharply after 2004. The present study was performed to show the clinical features of Korean patients with LAM, and to establish the reason for the recent increase in the diagnosis. All 63 patients were women and the mean age at diagnosis was 36 yr. The most common presenting symptom was dyspnea and 8 patients had tuberous sclerosis complex. The survival rate at 5 yr after diagnosis was 84%. Compared with patients diagnosed after 2004 (n=34), the patients diagnosed before 2004 (n=29) complained with dyspnea more (P=0.016) and had lower FEV(1)% predicted (P=0.003), and DLco% predicted (P=0.042). The higher proportion of patients diagnosed after 2004 showed the normal chest radiography, and they were detected by routine chest CT screening (P=0.016). This study showed that clinical features of Korean patients with LAM were not different from those reported elsewhere. It is concluded that the reason for the increase of newly diagnosed patients is the result of increase in detection of the early stage LAM by the widespread use of chest CT screening. ; McCormack FX, 2008, CHEST, V133, P507, DOI 10.1378/chest.07-0898 ; Bissler JJ, 2008, NEW ENGL J MED, V358, P140 ; Johnson SR, 2006, EUR RESPIR J, V27, P1056, DOI 10.1183/09031936.06.00113303 ; Ryu JH, 2006, AM J RESP CRIT CARE, V173, P105, DOI 10.1164/rccm.200409-1298OC ; Johnson SR, 2000, THORAX, V55, P1052 ; Urban T, 1999, MEDICINE, V78, P321 ; Oh YM, 1999, THORAX, V54, P618 ; Chu SC, 1999, CHEST, V115, P1041 ; Kalassian KG, 1997, AM J RESP CRIT CARE, V155, P1183 ; KITAICHI M, 1995, AM J RESP CRIT CARE, V151, P527 ; TAYLOR JR, 1990, NEW ENGL J MED, V323, P1254 ; MULLER NL, 1990, RADIOLOGY, V175, P335 ; ELIASSON AH, 1989, CHEST, V96, P1352 ; CARRINGTON CB, 1977, AM REV RESPIR DIS, V116, P977 ; SILVERST.EF, 1974, AM J ROENTGENOL, V120, P832 ; 1 |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1011-8934 |
| Relation: | JOURNAL OF KOREAN MEDICAL SCIENCE; Vol.25 8; 1182-1186; http://hdl.handle.net/10371/76475 |
| DOI: | 10.3346/jkms.2010.25.8.1182 |
| الاتاحة: | http://hdl.handle.net/10371/76475 https://doi.org/10.3346/jkms.2010.25.8.1182 |
| رقم الانضمام: | edsbas.7DACA818 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 10118934 |
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| DOI: | 10.3346/jkms.2010.25.8.1182 |