Academic Journal
Lymphopenia in covid-19: γδ t cells-based therapeutic opportunities
| العنوان: | Lymphopenia in covid-19: γδ t cells-based therapeutic opportunities |
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| المؤلفون: | Lo Presti E., Dieli F., Meraviglia S. |
| المساهمون: | Lo Presti E., Dieli F., Meraviglia S. |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2021 |
| المجموعة: | IRIS Università degli Studi di Palermo |
| مصطلحات موضوعية: | COVID-19, Gamma delta T cells, SARS-CoV-2 |
| الوصف: | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection dysregulates the immune system by lymphopenia of B cells, monocytes, eosinophils, basophils, and cytotoxic cells such as CD8, γδ T cells, and natural killer (NK) cells. Despite many studies being conducted to better understand the effects of SARS-CoV-2 on the immune system, many mechanisms still remain unclear, hindering the development of novel therapeutic approaches and strategies to improve the host’s immune defense. This mini-review summarizes the findings on the role of γδ T cells in coronavirus disease 2019 (COVID-19), providing an overview of the excellent anti-viral therapeutic potential of γδ T cells, that had not yet been exploited in depth. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/34071430; info:eu-repo/semantics/altIdentifier/wos/WOS:000666718500001; volume:9; issue:6; firstpage:1; lastpage:9; numberofpages:9; journal:VACCINES; https://hdl.handle.net/10447/528070; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228064/ |
| DOI: | 10.3390/vaccines9060562 |
| الاتاحة: | https://hdl.handle.net/10447/528070 https://doi.org/10.3390/vaccines9060562 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228064/ |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.7CA0B631 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/vaccines9060562 |
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