Academic Journal
Toxicity Evaluation of Quantum Dots (ZnS and CdS) Singly and Combined in Zebrafish (Danio rerio)
| العنوان: | Toxicity Evaluation of Quantum Dots (ZnS and CdS) Singly and Combined in Zebrafish (Danio rerio) |
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| المؤلفون: | Matos, Beatriz, Martins, Marta, Samamed, Antonio Cid, Sousa, David, Ferreira, Isabel, Diniz, Mário S. |
| المساهمون: | DQ - Departamento de Química, UCIBIO - Applied Molecular Biosciences Unit, DCEA - Departamento de Ciências e Engenharia do Ambiente, MARE - Centro de Ciências do Mar e do Ambiente, LAQV@REQUIMTE, CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N), DCM - Departamento de Ciência dos Materiais |
| سنة النشر: | 2020 |
| المجموعة: | Repositório da Universidade Nova de Lisboa (UNL) |
| مصطلحات موضوعية: | CdS, oxidative stress, quantum dots, toxicity, zebrafish, ZnS, Public Health, Environmental and Occupational Health, Health, Toxicology and Mutagenesis, SDG 3 - Good Health and Well-being |
| الوصف: | This work was supported by the Applied Molecular Biosciences Unit- UCIBIO which is financed by national funds from FCT/MCTES (UID/Multi/04378/2019) and by the Associate Laboratory for Green Chemistry- LAQV which is financed by national funds from FCT/MCTES (UID/QUI/50006/2019) and by the Marine and Environmental Sciences Centre (MARE) which is financed by national funds from FCT/MCTES (UID/MAR/04292/2019). ; The exponential growth of nanotechnology has led to the production of large quantities of nanomaterials for numerous industrial, technological, agricultural, environmental, food and many other applications. However, this huge production has raised growing concerns about the adverse effects that the release of these nanomaterials may have on the environment and on living organisms. Regarding the effects of QDs on aquatic organisms, existing data is scarce and often contradictory. Thus, more information is needed to understand the mechanisms associated with the potential toxicity of these nanomaterials in the aquatic environment. The toxicity of QDs (ZnS and CdS) was evaluated in the freshwater fish Danio rerio. The fishes were exposed for seven days to different concentrations of QDs (10, 100 and 1000 µg/L) individually and combined. Oxidative stress enzymes (catalase, superoxide dismutase and glutathione S-transferase), lipid peroxidation, HSP70 and total ubiquitin were assessed. In general, results suggest low to moderate toxicity as shown by the increase in catalase activity and lipid peroxidation levels. The QDs (ZnS and CdS) appear to cause more adverse effects singly than when tested combined. However, LPO results suggest that exposure to CdS singly caused more oxidative stress in zebrafish than ZnS or when the two QDs were tested combined. Levels of Zn and Cd measured in fish tissues indicate that both elements were bioaccumulated by fish and the concentrations increased in tissues according to the concentrations tested. The increase in HSP70 measured in fish exposed to 100 µg ZnS-QDs/L may be ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1660-4601 |
| Relation: | PURE: 16497313; PURE UUID: 3c1f8e73-ff4f-470b-bda3-cf1f38628bf4; Scopus: 85077520967; PubMed: 31905638; PubMedCentral: PMC6981874; WOS: 000509391500232; ORCID: /0000-0002-0507-3394/work/70244116; ORCID: /0000-0002-8838-0364/work/74126975; http://hdl.handle.net/10362/97777; https://doi.org/10.3390/ijerph17010232 |
| DOI: | 10.3390/ijerph17010232 |
| الاتاحة: | http://hdl.handle.net/10362/97777 https://doi.org/10.3390/ijerph17010232 |
| Rights: | openAccess |
| رقم الانضمام: | edsbas.7AA20F79 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 16604601 |
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| DOI: | 10.3390/ijerph17010232 |