Academic Journal
Synthesis and evaluation of pyridine-derived bedaquiline analogues containing modifications at the A-ring subunit
العنوان: | Synthesis and evaluation of pyridine-derived bedaquiline analogues containing modifications at the A-ring subunit |
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المؤلفون: | Barbaro, Lisa, Nagalingam, Gayathri, Triccas, James A., Tan, Lendl, West, Nicholas P., Baell, Jonathan B., Priebbenow, Daniel L. |
المساهمون: | Australian Research Council, National Health and Medical Research Council |
المصدر: | RSC Medicinal Chemistry ; volume 12, issue 6, page 943-959 ; ISSN 2632-8682 |
بيانات النشر: | Royal Society of Chemistry (RSC) |
سنة النشر: | 2021 |
الوصف: | Unique synthetic strategies were developed access to new bedaquiline analogues, leading to the discovery that anti-tubercular activity could be retained following replacement of bedaquiline's quinoline A-ring subunit with pyridine heterocycles. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.1039/d1md00063b |
الاتاحة: | http://dx.doi.org/10.1039/d1md00063b http://pubs.rsc.org/en/content/articlepdf/2021/MD/D1MD00063B |
Rights: | http://rsc.li/journals-terms-of-use |
رقم الانضمام: | edsbas.7A784DFE |
قاعدة البيانات: | BASE |
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