Academic Journal
Synthesis and evaluation of pyridine-derived bedaquiline analogues containing modifications at the A-ring subunit
| العنوان: | Synthesis and evaluation of pyridine-derived bedaquiline analogues containing modifications at the A-ring subunit |
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| المؤلفون: | Barbaro, Lisa, Nagalingam, Gayathri, Triccas, James A., Tan, Lendl, West, Nicholas P., Baell, Jonathan B., Priebbenow, Daniel L. |
| المساهمون: | Australian Research Council, National Health and Medical Research Council |
| المصدر: | RSC Medicinal Chemistry ; volume 12, issue 6, page 943-959 ; ISSN 2632-8682 |
| بيانات النشر: | Royal Society of Chemistry (RSC) |
| سنة النشر: | 2021 |
| الوصف: | Unique synthetic strategies were developed access to new bedaquiline analogues, leading to the discovery that anti-tubercular activity could be retained following replacement of bedaquiline's quinoline A-ring subunit with pyridine heterocycles. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1039/d1md00063b |
| الاتاحة: | http://dx.doi.org/10.1039/d1md00063b http://pubs.rsc.org/en/content/articlepdf/2021/MD/D1MD00063B |
| Rights: | http://rsc.li/journals-terms-of-use |
| رقم الانضمام: | edsbas.7A784DFE |
| قاعدة البيانات: | BASE |
| DOI: | 10.1039/d1md00063b |
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