Academic Journal
Bypass surgery versus endovascular revascularization for occlusive infrainguinal peripheral artery disease: a meta-analysis of randomized controlled trials for the development of the Italian Guidelines for the treatment of diabetic foot syndrome
| العنوان: | Bypass surgery versus endovascular revascularization for occlusive infrainguinal peripheral artery disease: a meta-analysis of randomized controlled trials for the development of the Italian Guidelines for the treatment of diabetic foot syndrome |
|---|---|
| المؤلفون: | Scatena, Alessia, Apicella, Matteo, Mantuano, Michele, Liistro, Francesco, Ventoruzzo, Giorgio, Petruzzi, Pasquale, Miranda, Cesare, Monge, Luca, Ragghianti, Benedetta, Silverii, Antonio, Ferraro, Isabella, Uccioli, Luigi, Vermigli, Cristiana, Mannucci, Edoardo, Scevola, Germano, Stabile, Eugenio, Gargiulo, Mauro, Monami, Matteo |
| المساهمون: | Scatena, Alessia, Apicella, Matteo, Mantuano, Michele, Liistro, Francesco, Ventoruzzo, Giorgio, Petruzzi, Pasquale, Miranda, Cesare, Monge, Luca, Ragghianti, Benedetta, Silverii, Antonio, Ferraro, Isabella, Uccioli, Luigi, Vermigli, Cristiana, Mannucci, Edoardo, Scevola, Germano, Stabile, Eugenio, Gargiulo, Mauro, Monami, Matteo |
| سنة النشر: | 2024 |
| المجموعة: | IRIS Università degli Studi di Bologna (CRIS - Current Research Information System) |
| مصطلحات موضوعية: | Bypa, Critical-threatening limb ischemia, Diabete, Major amputation, Percutaneous transluminal angioplasty, Revascularization |
| الوصف: | To report a review and meta-analysis of all randomized controlled trials (RCTs) comparing bypass surgery (BS) and endovascular treatment (ET) in infrainguinal peripheral arterial disease (PAD) for several endpoints, such as major and minor amputation, major adverse limb events (MALEs), ulcer healing, time to healing, and all-cause mortality to support the development of the Italian Guidelines for the Treatment of Diabetic Foot Syndrome (DFS). A MEDLINE and EMBASE search was performed to identify RCTs, published since 1991 up to June 21, 2023, enrolling patients with lower limb ischemia due to atherosclerotic disease (Rutherford I-VI). Any surgical BS or ET was allowed, irrespective of the approach, route, or graft employed, from iliac to below-the-knee district. Primary endpoint was major amputation rate. Secondary endpoints were amputation-free survival major adverse limb events (MALEs), minor amputation rate, all-cause mortality, ulcer healing rate, time to healing, pain, transcutaneous oxygen pressure (TcPO2) or ankle-brachial index (ABI), quality of life, need for a new procedure, periprocedural serious adverse events (SAE; within 30 days from the procedure), hospital lenght of stay, and operative time. Twelve RCTs were included, one enrolled two separate cohorts of patients, and therefore, the studies included in the analyses were 13. Participants treated with ET had a similar rate of major amputations to participants treated with BS (MH-OR 0.85 [0.60, 1.20], p = 0.36); only one trial reported separately data on patients with diabetes (N = 1), showing no significant difference between ET and BS (MH-OR: 0.67 [0.09, 5.13], p = 0.70). For minor amputation, no between-group significant differences were reported: MH-OR for ET vs BS: 0.83 [0.21, 3.30], p = 0.80). No significant difference in amputation-free survival between the two treatment modalities was identified (MH-OR 0.94 [0.59, 1.49], p = 0.80); only one study reported subgroup analyses on diabetes, with a non-statistical trend toward reduction in favor ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | ELETTRONICO |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/37792028; info:eu-repo/semantics/altIdentifier/wos/WOS:001079989200001; volume:61; issue:1; firstpage:19; lastpage:28; numberofpages:10; journal:ACTA DIABETOLOGICA; https://hdl.handle.net/11585/952013; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85173486520; https://link.springer.com/article/10.1007/s00592-023-02185-x |
| DOI: | 10.1007/s00592-023-02185-x |
| الاتاحة: | https://hdl.handle.net/11585/952013 https://doi.org/10.1007/s00592-023-02185-x https://link.springer.com/article/10.1007/s00592-023-02185-x |
| رقم الانضمام: | edsbas.78F3DA64 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s00592-023-02185-x |
|---|