Academic Journal
Scaling-up engineering biology for enhanced environmental solutions
| العنوان: | Scaling-up engineering biology for enhanced environmental solutions |
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| المؤلفون: | Hassard, Francis, Curtis, Thomas P, Dotro, Gabriela C, Golyshin, Peter, Gutierrez, Tony, Heaven, Sonia, Horsfall, Louise, Jefferson, Bruce, Jones, Davey L, Krasnogor, Natalio, Kumar, Vinod, Lea-Smith, David J, Le Corre Pidou, Kristell, Liu, Yongqiang, Lyu, Tao, McCarthy, Ronan R, McKew, Boyd, Smith, Cindy, Yakunin, Alexander, Yang, Zhugen, Zhang, Yue, Coulon, Frederic |
| بيانات النشر: | American Chemical Society |
| سنة النشر: | 2024 |
| الوصف: | Synthetic biology (SynBio) offers transformative solutions for addressing environmental challenges by engineering organisms capable of degrading pollutants, enhancing carbon sequestration, and valorizing waste (Figure 1). These innovations hold the potential to revolutionize bioremediation strategies, ecosystem restoration, and sustainable environmental management. (1) Advances in SynBio, including automation, precise manipulation of genetic material, (2) and design of semisynthetic organisms with enhanced capabilities, can improve the efficiency of microbes for eliminating pollutants such as hydrocarbons and plastics or extracting valuable resources from the environment. (3) Genome editing technologies, such as CRISPR-Cas9, allows the editing of genomes with unprecedented accuracy, facilitating the development of organisms with desired traits or functions. (4) Furthermore, SynBio encompasses the engineering of metabolic enzymes within organisms, leading to the design of microbial factories capable of degrading complex and persistent chemicals, and converting waste to valuable resources. (5) These advancements also facilitate the manipulation of bacterial social behaviors, offering the capacity for tunable control at the multicellular level and engineered biofilms. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | |
| اللغة: | English |
| تدمد: | 2161-5063 |
| Relation: | ispartof: ACS synthetic biology spage 1586 epage 1588 issue 6 vol 13; PMC11197081; WOS:001253015300001; 991005686561007891; https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Scaling-up-engineering-biology-for-enhanced-environmental/991005686561007891; https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12165485050007891/13165507760007891; alma:61MUN_INST/bibs/991005686561007891 |
| DOI: | 10.1021/acssynbio.4c00292 |
| الاتاحة: | https://doi.org/10.1021/acssynbio.4c00292 https://researchportal.murdoch.edu.au/esploro/outputs/journalArticle/Scaling-up-engineering-biology-for-enhanced-environmental/991005686561007891 https://researchportal.murdoch.edu.au/view/delivery/61MUN_INST/12165485050007891/13165507760007891 |
| Rights: | © 2024 The Authors ; Open ; CC BY V4.0 |
| رقم الانضمام: | edsbas.783DE3F7 |
| قاعدة البيانات: | BASE |
| تدمد: | 21615063 |
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| DOI: | 10.1021/acssynbio.4c00292 |