Academic Journal
Investigation of the Effects of Long-Term Methylphenidate Use on Growth and Bone Density in Children and Adoles with Diagnosis of Attention Deficit Hyperactivity Disorder ; Dikkat Eksikliği ve Hiperaktivite Bozukluğu Tanısı Alan Çocuk ve Ergenlerde Uzun Süreli Metilfenidat Kullanımının Büyüme ve Kemik Yoğunluğu Üzerine Etkilerinin Araştırılması
| العنوان: | Investigation of the Effects of Long-Term Methylphenidate Use on Growth and Bone Density in Children and Adoles with Diagnosis of Attention Deficit Hyperactivity Disorder ; Dikkat Eksikliği ve Hiperaktivite Bozukluğu Tanısı Alan Çocuk ve Ergenlerde Uzun Süreli Metilfenidat Kullanımının Büyüme ve Kemik Yoğunluğu Üzerine Etkilerinin Araştırılması |
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| المؤلفون: | ŞAHİN, Zeynep Anıl, ŞAHİN, İsmail Gökhan, BOZATLI, Leyla, GÖRKER, Işık |
| المصدر: | Volume: 9, Issue: 3 208-214 ; 2148-8118 ; 2618-6020 ; Muğla Sıtkı Koçman Üniversitesi Tıp Dergisi ; Medical Journal of Mugla Sitki Kocman University |
| بيانات النشر: | Muğla Sıtkı Koçman Üniversitesi Mugla Sitki Kocman University |
| سنة النشر: | 2021 |
| المجموعة: | DergiPark Akademik (E-Journals) |
| مصطلحات موضوعية: | Bone Development, Absorptiometry, ADDH, Methylphenidate, Absorptiometri, DEHB, Kemik Büyümesi, Metilfenidat, Tıp, Medicine |
| الوصف: | Our aim in this study is to investigate the effects of methylphenidate, which is the most commonly used pharmacological treatment agent, on growth and bone structure in patients with Attention Deficit Hyperactivity Disorder (ADHD). Patients with the diagnosis of ADHD was followed; 30 male cases were included in the study as a case group and compared with the control group in the similar age group. Groups; age (years), height (cm), body weight (kg) and body mass index (kg/m2), 25-hydroxycholecalciferol (Vitamin D), serum calcium values (mg/dl) and DEXA (Dual energy x-ray absorptiometry) compared with the results. In our study, no statistically significant difference was found between the groups in terms of growth parameters, Vitamin D levels, lumbar and hip bone mineral density. Serum calcium levels, proximal femur and lumbar vertebra Z scores were found to be statistically significantly lower in the case group (p=0.001; p=0.013; p=0.015). Methylphenidate treatment is the gold standard pharmacological treatment in ADHD cases. In no study in the literature, better growth parameters and bone density were found in ADHD cases compared to the control group due to the use of methylphenidate. Consistent with the literature, no difference was found between the groups in terms of growth parameters in our study. In bone parameters, hip and lumbar vertebra Z scores and serum calcium levels were found to be statistically significantly lower in the case group. Although we did not find a statistically significant difference between the groups in terms of vitamin D levels, we think that it is important that our case group conforms to the definition of Vitamin D deficiency and that our control group complies with the definition of Vitamin D deficiency in terms of mean values. ; Bu çalışmamızdaki amacımız, Dikkat Eksikliği ve Hiperaktivite Bozukluğu (DEHB) tanılı olgularda en sık kullandığımız farmakolojik tedavi ajanı olan metilfenidatın büyüme ve kemik yapısı üzerine etkilerini araştırmaktır. Trakya Üniversitesi Tıp Fakültesi, ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Turkish |
| Relation: | https://dergipark.org.tr/tr/download/article-file/1735535; https://dergipark.org.tr/tr/pub/muskutd/issue/74280/928527 |
| DOI: | 10.47572/muskutd.928527 |
| الاتاحة: | https://dergipark.org.tr/tr/pub/muskutd/issue/74280/928527 https://doi.org/10.47572/muskutd.928527 |
| رقم الانضمام: | edsbas.77EBB3F1 |
| قاعدة البيانات: | BASE |
| DOI: | 10.47572/muskutd.928527 |
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