التفاصيل البيبلوغرافية
| العنوان: |
Bi(OAc) 3 /Chiral Phosphoric Acid-Catalyzed Enantioselective 1,2- and Formal 1,4-Allylation Reaction of β,γ-Unsaturated α‑Ketoesters |
| المؤلفون: |
Xiang-Shuai Liu (11705116), Yao Li (154923), Xin Li (51274) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Medicine, Microbiology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Evolutionary Biology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, subsequent anionic oxy, oac )< sub, homoallylic tertiary alcohols, catalyzed enantioselective 1, asymmetric formal 1, formal 1, enantioselective 1, pot process, mild conditions, high enantioselectivity, good yields, excellent enantioselectivities, cope rearrangement, combined strategy |
| الوصف: |
A highly efficient asymmetric 1,2-allylation reaction of β,γ-unsaturated α-ketoesters was realized by using a Bi(OAc) 3 /chiral phosphoric acid catalyst system under mild conditions. Meanwhile, using this combined strategy of enantioselective 1,2-allylation and subsequent anionic oxy-Cope rearrangement, the asymmetric formal 1,4-allylation reaction was achieved by a one-pot process. These reactions offer rapid access to an array of homoallylic tertiary alcohols and γ-allyl-α-ketoesters with good yields and excellent enantioselectivities. Density functional theory calculations were conducted to interpret the high enantioselectivity. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/Bi_OAc_sub_3_sub_Chiral_Phosphoric_Acid-Catalyzed_Enantioselective_1_2-_and_Formal_1_4-Allylation_Reaction_of_-Unsaturated_Ketoesters/17013220 |
| DOI: |
10.1021/acs.orglett.1c03453.s001 |
| الاتاحة: |
https://doi.org/10.1021/acs.orglett.1c03453.s001 |
| Rights: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.77D08C7A |
| قاعدة البيانات: |
BASE |