Academic Journal
Effects of storage at -20°C on ischaemia-modified albumin results
| العنوان: | Effects of storage at -20°C on ischaemia-modified albumin results |
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| المؤلفون: | Beetham, R, Monk, C, Keating, L, Benger, J R, Kendall, J |
| المصدر: | Annals of Clinical Biochemistry: International Journal of Laboratory Medicine ; volume 43, issue 6, page 500-502 ; ISSN 0004-5632 1758-1001 |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2006 |
| الوصف: | Background: Ischaemia-modified albumin (IMA) is being studied as a new marker for reversible ischaemia in patients presenting with possible cardiac chest pain. The conditions under which samples are stored prior to analysis may be critical in influencing the analytical result and hence the cut-off used in any particular study. Methods: Sixty-eight samples taken during a study assessing the performance of IMA for risk stratification in patients presenting with possible cardiac chest pain were analysed both within 2.5 h of collection and after periods of storage at -20°C. Results: Samples stored at -20°C yielded IMA values on average 3 units higher than those analysed within 2.5 h (mean 90.5 vs. 87.5; P < 0.00001). A Bland-Altman plot showed that the difference was not concentration dependent. Conclusions: These results indicate that decision cut-offs will be influenced by conditions of sample storage prior to IMA analysis, and that these should be stated in detail for each study. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1258/000456306778904669 |
| الاتاحة: | https://doi.org/10.1258/000456306778904669 https://journals.sagepub.com/doi/pdf/10.1258/000456306778904669 |
| Rights: | https://journals.sagepub.com/page/policies/text-and-data-mining-license |
| رقم الانضمام: | edsbas.76C74106 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1258/000456306778904669 |
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