التفاصيل البيبلوغرافية
| العنوان: |
Outcome of decompressive craniectomy in comparison to nonsurgical treatment in patients with malignant MCA infarction |
| المؤلفون: |
Rahmanian, Abdolkarim, Seifzadeh, Babak, Razmkon, Ali, Petramfar, Peyman, Kivelev, Juri, Alibai, Ehsan-Ali, Hernesniemi, Juha |
| المساهمون: |
Department of Neurosciences, Neurokirurgian yksikkö, Clinicum |
| بيانات النشر: |
Springer International Publishing AG |
| سنة النشر: |
2016 |
| المجموعة: |
Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| مصطلحات موضوعية: |
Cerebral infarction, Decompressive craniectomy, Middle cerebral artery, MIDDLE CEREBRAL-ARTERY, HEAD-INJURY, HEMICRANIECTOMY, SURGERY, EXPERIENCE, DUROTOMY, DESTINY, STROKE, Neurology and psychiatry, anesthesiology, intensive care, radiology |
| الوصف: |
Background: Malignant cerebral infarction is a well-recognized disease, comprising 10-15% of all cases with cerebral infarction and causing herniation and death in 80% of cases. In this study, we compare the effects of decompressive craniectomy versus conventional medical treatment on mortality rate and functional and neurological outcome in patients with malignant MCA infarction. Methods: We performed a prospective case-control study on 60 patients younger than 80years of age suffering malignant MCA cerebral infarction. The case group underwent decompressive craniectomy in addition to routine aggressive medical care; while the control group received routine medical treatment. Patient outcome was assessed using Glasgow outcome scale and modified Rankin scale within three months of follow-up. The data were analyzed by SPSS version 16.0 software using Chi Square, One-way ANOVA and Mann-Whitney tests. Results: There were 27 male and 33 female patients with a mean age of 60.6 years (SD = 12.3). Glasgow outcome scale score averaged 2.93 in the surgical versus 1.53 in the medical group; this difference was significant (p = 0.001). Outcome in modified Rankin scale was also significantly lower in the surgical (3.27) versus medical (5.27) group (p <0.001). Surgery could decrease the mortality rate about 47%. Conclusion: In this study, decompressive craniectomy could decrease mortality rate, and improve neurological and functional outcome, and decrease long-term disability in patients with malignant MCA infarction. ; Peer reviewed |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
Rahmanian , A , Seifzadeh , B , Razmkon , A , Petramfar , P , Kivelev , J , Alibai , E-A & Hernesniemi , J 2014 , ' Outcome of decompressive craniectomy in comparison to nonsurgical treatment in patients with malignant MCA infarction ' , SpringerPlus , vol. 3 , 115 . https://doi.org/10.1186/2193-1801-3-115; http://hdl.handle.net/10138/165515; c2f07f71-c22d-4cc1-af48-1bbd71c09563; 84899498385; 000358952400002 |
| الاتاحة: |
http://hdl.handle.net/10138/165515 |
| Rights: |
cc_by ; info:eu-repo/semantics/openAccess ; openAccess |
| رقم الانضمام: |
edsbas.76907CBF |
| قاعدة البيانات: |
BASE |