Academic Journal

接种S180肉瘤的小鼠肿瘤组织和器官中组蛋白与正常小鼠的比较研究 ; Comparative to the Histone Derived from the S180-Transplanted Mice and the Normal Mouse

التفاصيل البيبلوغرافية
العنوان: 接种S180肉瘤的小鼠肿瘤组织和器官中组蛋白与正常小鼠的比较研究 ; Comparative to the Histone Derived from the S180-Transplanted Mice and the Normal Mouse
المؤلفون: 李俊燕, 周克夫, 何晶
سنة النشر: 2006
المجموعة: Xiamen University Institutional Repository
مصطلحات موضوعية: 组蛋白H1, S180肉瘤, 酸抽提, SDS-PAGE, histone H1, S180 tumor, acid-extraction
الوصف: 采用酸抽提法分别提取接种S180肉瘤的小鼠肿瘤组织以及肝、脾、肾等器官的组蛋白和正常小鼠相应组织和器官的组蛋白,并采用SDS-PAGE方法进行检测.结果表明,正常小鼠的肝、脾、肾等器官提取的组蛋白在检测中可以看到组蛋白H1的亚带,而接种了S180肉瘤的小鼠的肿瘤组织以及肝、脾、肾等器官的组蛋白在检测中基本无明显的条带.这说明发生在小鼠身上的S180肿瘤组织对小鼠的肝、脾、肾组织中的组蛋白产生一定影响. ; The histone H1 is a kind of alkalescence protein,which plays an important role in the expression of gene.The histones from tumor tissues and liver,spleen,kidney of S180-transplanted mice and the same apparatus and tissues of normal mouse were extracted by acid-extraction and detected by SDS-PAGE electrophoresis.The results showed that histone H1 second-strips were detected obviously from normal mouse' liver,spleen and kidney,but there were not obvious histones from tumor tissues and liver,spleen,kidney of S180-transplanted mice comparatively,which suggest that the tumor tissues of the S180-transplanted mice could affect the histone level of their own apparatus and tissues,such as liver,spleen and kidney. ; 厦门大学细胞生物学和肿瘤细胞工程教育部重点实验室开放基金(2005108)资助
نوع الوثيقة: article in journal/newspaper
اللغة: Chinese
تدمد: 0438-0479
Relation: 厦门大学学报(自然科学版),2006,(S1):153-155; XDZK2006S1035; http://dspace.xmu.edu.cn/handle/2288/153749
الاتاحة: http://dspace.xmu.edu.cn/handle/2288/153749
رقم الانضمام: edsbas.765FB710
قاعدة البيانات: BASE