Academic Journal
Effects of Gadolinium Chelate Administration Timing on T2-weighted and Diffusion-weighted Abdominal MRI Examination: A Prospective Study
| العنوان: | Effects of Gadolinium Chelate Administration Timing on T2-weighted and Diffusion-weighted Abdominal MRI Examination: A Prospective Study |
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| المؤلفون: | Jia, Su-Lan, Xu, Hui, Yang, Da-Wei, Ren, A-Hong, Yang, Zheng-Han |
| المساهمون: | National Natural Science Foundation of China, Capital's Funds for Health Improvement and Research, Beijing, China |
| المصدر: | Current Medical Imaging Reviews ; volume 20 ; ISSN 1573-4056 |
| بيانات النشر: | Bentham Science Publishers Ltd. |
| سنة النشر: | 2024 |
| الوصف: | Background: Magnetic Resonance Imaging (MRI) data acquisition includes several sequences that might be optimized to reduce the scan time. Objective: This study aimed to investigate the impact of gadolinium chelate administration timing on scan duration and image quality in Diffusion-weighted Imaging (DWI) and T2-weighted Imaging (T2WI) during abdominal MRI examinations. Methods: A prospective study was conducted from October 2018 to May 2020. Study participants were assigned into a conventional group, undergoing MRI with DWI and T2WI sequences pre and post-gadolinium injection, or an optimized group, receiving MRI with DWI and T2WI sequences after gadolinium injection. Quantitative image quality, measured by the Signal-to-noise Ratio (SNR), Contrast-to-noise Ratio (CNR), and Apparent Diffusion Coefficient (ADC), was analyzed. Kappa statistics were employed for the inter-observer agreement on liver lesion detection. Results: Our study has included 341 patients, with 168 and 173 in the conventional and optimized groups, respectively. Mean scan durations were 1,304 (±143) and 1,015 (±129) s for the conventional and optimized groups, respectively (p<0.05). For the liver, spleen, and pancreas, SNR and ADC remained statistically unchanged in post-enhanced DWI and T2WI (p>0.05). Significant decreases in the SNR and ADC of the kidney were observed in post-contrast DWI and T2WI (p<0.05). Hepatic lesion detectability did not show significant differences between pre and post-contrast DWI and T2WI images (p>0.05). Conclusion: DWI and T2WI sequences assessed post-gadolinium administration exhibited shortened scan time without compromising the image quality for liver, spleen, and pancreas evaluations. However, these sequences should be examined before gadolinium administration when assessing the kidneys. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.2174/0115734056308153240817160848 |
| الاتاحة: | http://dx.doi.org/10.2174/0115734056308153240817160848 https://www.eurekaselect.com/article/download/235979 https://www.eurekaselect.com/235979/article |
| Rights: | https://creativecommons.org/licenses/by/4.0/legalcode |
| رقم الانضمام: | edsbas.762475DB |
| قاعدة البيانات: | BASE |
| DOI: | 10.2174/0115734056308153240817160848 |
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