Academic Journal
Male genital lichen sclerosus and filaggrin
| العنوان: | Male genital lichen sclerosus and filaggrin |
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| المؤلفون: | Shim, T. N., Brown, S. J., Francis, N. D., Dinneen, M., Hawkins, D., Muneer, A., Minhas, S., McLean, W. H. Irwin, Bunker, C. B. |
| المصدر: | Shim , T N , Brown , S J , Francis , N D , Dinneen , M , Hawkins , D , Muneer , A , Minhas , S , McLean , W H I & Bunker , C B 2019 , ' Male genital lichen sclerosus and filaggrin ' , Clinical and Experimental Dermatology , vol. 45 , no. 1 , pp. 127-128 . https://doi.org/10.1111/ced.14023 |
| سنة النشر: | 2019 |
| المجموعة: | Discovery - University of Dundee Online Publications |
| مصطلحات موضوعية: | /dk/atira/pure/subjectarea/asjc/2700/2708, name=Dermatology |
| الوصف: | Lichen sclerosus (LSc) is an acquired cutaneous disease of contentious aetiology. The majority of male cases involve the genitalia. Amongst prior postulated pathogenic factors in genital (G)LSc are infection, autoimmunity and genetic and environmental influences.1 There is an arguement that male (M)GLSc might be due to chronic occluded exposure of susceptible epithelium to urine. GLSc has also been associated with atopy.2 Filaggrin is a key epithelial protein expressed during terminal differentiation of the epidermis, forming a component of the epithelial barrier. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://discovery.dundee.ac.uk/en/publications/7a1cc44e-e43b-4bfc-a4b1-68d3a0accffd |
| DOI: | 10.1111/ced.14023 |
| الاتاحة: | https://discovery.dundee.ac.uk/en/publications/7a1cc44e-e43b-4bfc-a4b1-68d3a0accffd https://doi.org/10.1111/ced.14023 https://discovery.dundee.ac.uk/ws/files/35097173/MGLSc_filaggrin_CED_SHIM_Revision_2.pdf http://www.scopus.com/inward/record.url?scp=85068596674&partnerID=8YFLogxK |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.75C6BC9C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/ced.14023 |
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