التفاصيل البيبلوغرافية
| العنوان: |
Cortical Auditory Evoked Potentials in Children with Prenatal Exposure to Zika Virus |
| المؤلفون: |
Laís Cristine Delgado da Hora, Lilian Ferreira Muniz, Leonardo Gleygson Angelo Venâncio, Karina Paes Advíncula, Jéssica Dayane da Silva, Diana Babini Lapa de Albuquerque Britto, Demócrito de Barros Miranda Filho, Elizabeth B. Brickley, Ricardo Arraes de Alencar Ximenes, Silvio da Silva Caldas Neto, Mariana de Carvalho Leal |
| المصدر: |
Viruses; Volume 14; Issue 9; Pages: 1923 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
Zika virus, congenital infection, Congenital Zika Syndrome, microcephaly, Evoked Potentials, auditory, electrophysiology, auditory cortex, hearing, child development |
| جغرافية الموضوع: |
agris |
| الوصف: |
Prenatal exposure to ZIKV can cause neurologic and auditory damage. The electrophysiological responses obtained by Cortical Auditory Evoked Potentials (CAEP) may provide an objective method to investigate the function of cortical auditory pathways in children exposed to ZIKV. This case series analyzed the findings of CAEP in prenatal-period ZIKV-exposed children with and without microcephaly. The CAEP was performed in a total of 24 children. Five magnetic resonance imaging (MRI) images of the inner ear and brain of microcephalic children were analyzed and compared with CAEP measurements. Ventriculomegaly (80%), cortical/subcortical calcification (80%), and brain reduction (60%) were the most common alterations in the MRI. The P1-N1-P2 complex of the CAEP was observed in all children evaluated. The peak N2 was absent in two children. In the comparison of the CAEP measurements between the groups, children with microcephaly presented a higher amplitude of P2 (p = 0.017), which may reflect immaturity of the auditory pathways. Microcephalic and normocephalic children with prenatal exposure to ZIKV presented with the mandatory components of the CAEPs, regardless of changes in the CNS, suggesting that this population has, to some extent, the cortical ability to process sound stimuli preserved. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
Human Virology and Viral Diseases; https://dx.doi.org/10.3390/v14091923 |
| DOI: |
10.3390/v14091923 |
| الاتاحة: |
https://doi.org/10.3390/v14091923 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.7530A4DE |
| قاعدة البيانات: |
BASE |