Academic Journal
Unmasking Bartonella henselae infection in the shadows of long COVID thanks to clinical metagenomics
| العنوان: | Unmasking Bartonella henselae infection in the shadows of long COVID thanks to clinical metagenomics |
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| المؤلفون: | Aubry, Aurélien, Corvilain, Emilie, Ghelfenstein-Ferreira, Théo, Camelena, François, Meignin, Véronique, Berçot, Béatrice, Le Goff, Jérôme, Salmona, Maud |
| المساهمون: | Laboratoire de Virologie CHU Saint-Louis, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 (AGIR ), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Service d'Immunopathologie Hôpital Saint-Louis, Paris, Hopital Saint-Louis AP-HP (AP-HP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité), Laboratoire de Parasitologie-Mycologie CHU Saint Louis, Paris, Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal Paris, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Immunologie humaine, physiopathologie & immunothérapie (HIPI (UMR_S_976 / U976)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité) |
| المصدر: | ISSN: 0934-9723. |
| بيانات النشر: | HAL CCSD Springer Verlag |
| سنة النشر: | 2024 |
| مصطلحات موضوعية: | Metagenomics, Long COVID, Bartonellosis, Cat scratch disease, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology |
| الوصف: | International audience ; The diagnosis of long COVID often relies on symptoms post-COVID-19, occasionally lacking biological evidence. This case study illustrates how investigating long COVID uncovered an underlying bartonellosis through clinical metagenomics. Following mild COVID-19, a 26-year-old woman experienced persistent symptoms during 5 months, including axillary adenopathy. Pathological examination, 16 S rRNA PCR, and clinical metagenomic analysis were done on an adenopathy biopsy. The latter revealed Bartonella henselae DNA and RNA. Treatment with clarithromycin improved symptoms. This case underscores the relevance of clinical metagenomics in diagnosing hidden infections. Post-COVID symptoms warrant thorough investigation, and bartonellosis should be considered in polyadenopathy cases, regardless of a recent history of cat or flea exposures. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-04562918; https://hal.science/hal-04562918 |
| DOI: | 10.1007/s10096-024-04801-2 |
| الاتاحة: | https://hal.science/hal-04562918 https://doi.org/10.1007/s10096-024-04801-2 |
| رقم الانضمام: | edsbas.74F22156 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s10096-024-04801-2 |
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