Academic Journal
The Laboratory Automation Protocol (LAP) Format and Repository: A Platform for Enhancing Workflow Efficiency in Synthetic Biology
| العنوان: | The Laboratory Automation Protocol (LAP) Format and Repository: A Platform for Enhancing Workflow Efficiency in Synthetic Biology |
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| المؤلفون: | Anhel, Ana-Mariya, Alejaldre, Lorea, Goñi-Moreno, Ángel |
| المساهمون: | Comunidad de Madrid, Agencia Estatal de Investigación (España), Ministerio de Ciencia e Innovación (España), European Commission, Anhel, Ana-Mariya, Alejaldre, Lorea, Goñi-Moreno, Ángel |
| بيانات النشر: | American Chemical Society |
| سنة النشر: | 2023 |
| المجموعة: | Digital.CSIC (Consejo Superior de Investigaciones Científicas / Spanish National Research Council) |
| مصطلحات موضوعية: | Automation, Protocol, Repository, Standard |
| الوصف: | 7 Pág. ; Laboratory automation deals with eliminating manual tasks in high-throughput protocols. It therefore plays a crucial role in allowing fast and reliable synthetic biology. However, implementing open-source automation solutions often demands experimental scientists to possess scripting skills, and even when they do, there is no standardized toolkit available for their use. To address this, we present the Laboratory Automation Protocol (LAP) Format and Repository. LAPs adhere to a standardized script-based format, enhancing end-user implementation and simplifying further development. With a modular design, LAPs can be seamlessly combined to create customized, target-specific workflows. Furthermore, all LAPs undergo experimental validation, ensuring their reliability. Detailed information is provided within each repository entry, allowing users to validate the LAPs in their own laboratory settings. We advocate for the adoption of the LAP Format and Repository as a community resource, which will continue to expand, improving the reliability and reproducibility of the automation processes. ; This work was supported by the grants BioSinT-CM (Y2020/TCS-6555) and CONTEXT (Atracción de Talento Program; 2019-T1/BIO-14053) Projects of the Comunidad de Madrid, MULTI-SYSBIO (PID2020-117205GA-I00) and the Severo Ochoa Program for Centres of Excellence in R&D (CEX2020-000999-S) funded by MCIN/AEI/10.13039/501100011033, and the ECCO (ERC-2021-COG-101044360) contract of the EU. ; With funding from the Spanish government through the ‘Severo Ochoa Centre of Excellence’ accreditation (CEX2020‐000999‐S) ; Peer reviewed |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2161-5063 |
| Relation: | #PLACEHOLDER_PARENT_METADATA_VALUE#; S2020/TCS-6555; S2019-T1/BIO-14053; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-117205GA-I00/ES/IMPLEMENTAR RELACIONES SOCIALES EN SISTEMAS MULTICELULARES SINTETICOS PARA ALCANZAR BIOCOMPUTACIONES ROBUSTAS Y FIABLES /; info:eu-repo/grantAgreement/EC//ERC-2021-COG-101044360; Centro de Biotecnología y Genómica de Plantas (CBGP); Publisher's version; https://doi.org/10.1021/acssynbio.3c00397; Sí; ACS Synthetic Biology 12(12): 3514-3520 (2023); CEX2020-000999-S; http://hdl.handle.net/10261/348118; http://dx.doi.org/10.13039/501100004837; http://dx.doi.org/10.13039/501100011033; http://dx.doi.org/10.13039/100012818; http://dx.doi.org/10.13039/501100000780; 2-s2.0-85179168720; https://api.elsevier.com/content/abstract/scopus_id/85179168720 |
| DOI: | 10.1021/acssynbio.3c00397 |
| DOI: | 10.13039/501100004837 |
| DOI: | 10.13039/501100011033 |
| DOI: | 10.13039/100012818 |
| DOI: | 10.13039/501100000780 |
| الاتاحة: | http://hdl.handle.net/10261/348118 https://doi.org/10.1021/acssynbio.3c00397 https://doi.org/10.13039/501100004837 https://doi.org/10.13039/501100011033 https://doi.org/10.13039/100012818 https://doi.org/10.13039/501100000780 https://api.elsevier.com/content/abstract/scopus_id/85179168720 |
| Rights: | open |
| رقم الانضمام: | edsbas.73DA931B |
| قاعدة البيانات: | BASE |
| تدمد: | 21615063 |
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| DOI: | 10.1021/acssynbio.3c00397 |