Academic Journal

SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound Sparus aurata Skin

التفاصيل البيبلوغرافية
العنوان: SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound Sparus aurata Skin
المؤلفون: Isabel M. Cerezo, Olivia Pérez-Gómez, Rocio Bautista, Pedro Seoane, M. Ángeles Esteban, M. Carmen Balebona, Miguel A. Moriñigo, Silvana T. Tapia-Paniagua
المصدر: Animals; Volume 13; Issue 2; Pages: 193
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2023
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: aquaculture, fish, gilthead seabream, microbiota, probiotic, RNA seq, skin, wound
جغرافية الموضوع: agris
الوصف: Skin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deeply. The wounded specimens that received the diet with SpPdp11 showed a decrease in the abundance of Enterobacteriaceae, Photobacterium and Achromobacter related to bacterial biofilm formation, as well as the overexpression of genes involved in signaling mechanisms (itpr3), cell migration and differentiation (panxa, ttbk1a, smpd3, vamp5); and repression of genes related to cell proliferation (vstm4a, areg), consistent with a more efficient skin healing processes than that observed in the wounded control group. In addition, among the groups of damaged skin with different diets, Achromobacter, f_Ruminococcaceae, p_Bacteroidetes, Fluviicola and Flavobacterium genera with significant differences showed positive correlations with genes related to cell migration and negative correlations with inflammation and cell proliferation and may be the target of future studies.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: Aquatic Animals; https://dx.doi.org/10.3390/ani13020193
DOI: 10.3390/ani13020193
الاتاحة: https://doi.org/10.3390/ani13020193
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.735C3974
قاعدة البيانات: BASE