Academic Journal

Radiofrequency Ablation of Indeterminate Thyroid Nodules: The First North American Comparative Analysis

التفاصيل البيبلوغرافية
العنوان: Radiofrequency Ablation of Indeterminate Thyroid Nodules: The First North American Comparative Analysis
المؤلفون: Peter P. Issa, Mahmoud Omar, Chad P. Issa, Yusef Buti, Mohammad Hussein, Mohamed Aboueisha, Ali Abdelhady, Mohamed Shama, Grace S. Lee, Eman Toraih, Emad Kandil
المصدر: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11493
بيانات النشر: Multidisciplinary Digital Publishing Institute
سنة النشر: 2022
المجموعة: MDPI Open Access Publishing
مصطلحات موضوعية: radiofrequency ablation, RFA, indeterminate thyroid nodules, thyroid, Bethesda III, Bethesda IV
جغرافية الموضوع: agris
الوصف: Thyroid nodules can be classified as benign, malignant, or indeterminate, the latter of which make up 10–30% of nodules. Radiofrequency ablation (RFA) has become an attractive and promising therapy for the treatment of benign thyroid nodules. However, few studies have investigated the safety and efficacy of RFA for the management of indeterminate thyroid nodules. In this study, 178 patients with thyroid nodules diagnosed as benign (Bethesda II) or indeterminate (Bethesda III/IV) by preoperative cytopathological analysis were included. Patients in the benign and indeterminate cohorts had similar thyroid nodule volume reduction rates at 65.60% and 64.20%, respectively (p = 0.68). The two groups had similar nodular regrowth rates, at 11.2% for benign nodules and 9.40% for indeterminate nodules (p = 0.72). A total of three cases of transient dysphonia were reported. RFA of indeterminate thyroid nodules was comparable to that of benign thyroid nodules in all parameters of interest, including volume reduction rate. To our best knowledge, our work is the first North American analysis comparing benign and indeterminate thyroid nodules and suggests RFA to be a promising modality for the management of indeterminate thyroid nodules.
نوع الوثيقة: text
وصف الملف: application/pdf
اللغة: English
Relation: Molecular Endocrinology and Metabolism; https://dx.doi.org/10.3390/ijms231911493
DOI: 10.3390/ijms231911493
الاتاحة: https://doi.org/10.3390/ijms231911493
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.72EC79F5
قاعدة البيانات: BASE