Academic Journal
Alkaloid profiling of Galanthus woronowii Losinsk. by GC-MS and evaluation of its biological activity
| العنوان: | Alkaloid profiling of Galanthus woronowii Losinsk. by GC-MS and evaluation of its biological activity |
|---|---|
| المؤلفون: | Onur, Mustafa Ali, Berkov, Strahil, Bastida, Jaume, Unver Somer, Nehir, Bozkurt, Buket, Emir, Ahmet, Kaya, Gulen Irem |
| بيانات النشر: | Marmara Univ, Fac Pharmacy |
| سنة النشر: | 2017 |
| المجموعة: | Ege University Institutional Repository |
| مصطلحات موضوعية: | Amaryllidaceae, Galanthus woronowii, GC-MS, alkaloids |
| الوصف: | WOS: 000417369600022 ; The alkaloid profiles of the aerial parts and the bulbs of Galanthus woronowii Losinsk. were analyzed by means of Gas Chromatography-Mass Spectrometry (GC-MS). Totally, twenty-eight compounds were detected. Galanthamine and galanthine were found to be the main alkaloids both in the extracts of the aerial parts and the bulbs. Most of the identified compounds were lycorine and galanthamine-type Amaryllidaceae alkaloids. In addition, the acetylcholinesterase (AChE) inhibitor potentials of the extracts prepared from the aerial parts and bulbs were determined by in vitro Ellman's method and both of the extracts were found to exhibit significant activity (aerial parts: IC50 = 0.027 mu g/mL and bulbs: IC50 = 0.084 mu g/mL). ; This study was financially supported by Ege University Research Fund (Project No: 09/ECZ/021 and 09/ECZ/018) and partially supported by TUBITAK (104T272). ; Ege University Research FundEge University [09/ECZ/021, 09/ECZ/018]; TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [104T272] |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1309-0801 |
| Relation: | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; Marmara Pharmaceutical Journal; https://hdl.handle.net/11454/32750; https://doi.org/10.12991/mpj.2017.12; 21; 915; 920 |
| DOI: | 10.12991/mpj.2017.12 |
| الاتاحة: | https://hdl.handle.net/11454/32750 https://doi.org/10.12991/mpj.2017.12 |
| Rights: | open |
| رقم الانضمام: | edsbas.7238E102 |
| قاعدة البيانات: | BASE |
| تدمد: | 13090801 |
|---|---|
| DOI: | 10.12991/mpj.2017.12 |