التفاصيل البيبلوغرافية
| العنوان: |
Synthesis of Ortho -Functionalized 1,4-Cubanedicarboxylate Derivatives through Photochemical Chlorocarbonylation |
| المؤلفون: |
Diego E. Collin (10981921), Kristina Kovacic (10981924), Mark E. Light (730259), Bruno Linclau (1600804) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Medicine, Cell Biology, Genetics, Neuroscience, Biotechnology, Evolutionary Biology, Ecology, Developmental Biology, Mental Health, Infectious Diseases, Computational Biology, Chemical Sciences not elsewhere classified, cubane ring, regioselective ester hydrolysis, radical-mediated chlorocarbonylatio., 3 D benzene isostere, Photochemical Chlorocarbonylation |
| الوصف: |
The cubane ring has received intense attention as a 3D benzene isostere and scaffold. Mono- and 1,4-disubstituted cubanes are well-described. Here we report a practical procedure for a direct radical-mediated chlorocarbonylation process initially reported by Bashir-Hashemi, to access a range of 2-substituted 1,4-cubanedicarboxylic ester derivatives. A subsequent regioselective ester hydrolysis to give fully differentiated 1,2,4-trisubstituted cubanes is demonstrated. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/Synthesis_of_i_Ortho_i_-Functionalized_1_4-Cubanedicarboxylate_Derivatives_through_Photochemical_Chlorocarbonylation/14794336 |
| DOI: |
10.1021/acs.orglett.1c01702.s001 |
| الاتاحة: |
https://doi.org/10.1021/acs.orglett.1c01702.s001 |
| Rights: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.7202B64 |
| قاعدة البيانات: |
BASE |