التفاصيل البيبلوغرافية
| العنوان: |
A H 2 S‑Triggered Dual-Modal Second Near-Infrared/Photoacoustic Intelligent Nanoprobe for Highly Specific Imaging of Colorectal Cancer |
| المؤلفون: |
Shenghui Bi (10024832), Zhiming Deng (6541955), Qing Jiang (197843), Mingyang Jiang (4172821), Songjun Zeng (650531) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Medicine, Cell Biology, Biotechnology, Sociology, Cancer, Space Science, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, noninvasive intelligent detection, modal second near, highly specific imaging, diagnosing colorectal cancer, modal imaging strategy, ‑ triggered dual, photoacoustic intelligent nanoprobe, expressed endogenous h, 2 , modal nanoprobe, colorectal cancer, endogenous h, vivo <, situ <, colorectal tumor, triggered sio, modal nir, via dual, sulfuration reaction, rarely explored, comprehensive information, biosynthesis via |
| الوصف: |
An endogenous H 2 S-triggered intelligent optical nanoprobe combining second near-infrared (NIR-II) fluorescence with photoacoustic (PA) imaging can provide more comprehensive information to further improve the sensitivity and reliability of diagnosis for colorectal tumor, which is rarely explored. Herein, an endogenous H 2 S-triggered SiO 2 @Ag nanoprobe was designed for in situ dual-modal NIR-II/PA imaging of colorectal cancer. The designed dual-modal nanoprobe can be converted to SiO 2 @Ag 2 S after in situ biosynthesis via a sulfuration reaction with the over-expressed endogenous H 2 S in the colorectal tumor. More importantly, the designed SiO 2 @Ag nanoprobe exhibits high sensitivity and specificity for diagnosing colorectal cancer in vivo via dual-modal NIR-II/PA imaging. These results provide a new NIR-II/PA dual-modal imaging strategy for noninvasive intelligent detection of colorectal cancer. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/A_H_sub_2_sub_S_Triggered_Dual-Modal_Second_Near-Infrared_Photoacoustic_Intelligent_Nanoprobe_for_Highly_Specific_Imaging_of_Colorectal_Cancer/16671119 |
| DOI: |
10.1021/acs.analchem.1c02200.s001 |
| الاتاحة: |
https://doi.org/10.1021/acs.analchem.1c02200.s001 |
| Rights: |
CC BY-NC 4.0 |
| رقم الانضمام: |
edsbas.72000CC6 |
| قاعدة البيانات: |
BASE |