Academic Journal
Apremilast Normalizes Gene Expression of Inflammatory Mediators in Human Keratinocytes and Reduces Antigen-Induced Atopic Dermatitis in Mice
| العنوان: | Apremilast Normalizes Gene Expression of Inflammatory Mediators in Human Keratinocytes and Reduces Antigen-Induced Atopic Dermatitis in Mice |
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| المؤلفون: | Schafer, Peter H, Adams, Mary, Horan, Gerald, Truzzi, Francesca, Marconi, Alessandra, Pincelli, Carlo |
| المساهمون: | Schafer, Peter H, Adams, Mary, Horan, Gerald, Truzzi, Francesca, Marconi, Alessandra, Pincelli, Carlo |
| سنة النشر: | 2019 |
| المجموعة: | Archivio della ricerca dell'Università di Modena e Reggio Emilia (Unimore: IRIS) |
| الوصف: | Apremilast, an oral phosphodiesterase (PDE)4 inhibitor, has demonstrated efficacy in psoriasis, while its efficacy in atopic dermatitis (AD) was found to be modest. AD is a chronic inflammatory skin disease associated with activation of T helper (Th)2 and Th17 immunity and a compromised epidermal barrier. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/31598889; info:eu-repo/semantics/altIdentifier/wos/WOS:000509095400003; volume:19; firstpage:329; lastpage:338; numberofpages:10; journal:DRUGS IN R&D; http://hdl.handle.net/11380/1182980; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85074499617 |
| DOI: | 10.1007/s40268-019-00284-1 |
| الاتاحة: | http://hdl.handle.net/11380/1182980 https://doi.org/10.1007/s40268-019-00284-1 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.7120270 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s40268-019-00284-1 |
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