Academic Journal
Spanish consensus on treat to target for osteoporosis
| العنوان: | Spanish consensus on treat to target for osteoporosis |
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| المؤلفون: | Nogués Solán, Xavier, Nolla, J. M., Casado, E., Jódar, E., Muñoz-Torres, María Jesus, Quesada-Gómez, J. M., Canals, L., Balcells, M., Lizán, Luis |
| بيانات النشر: | Springer Verlag |
| سنة النشر: | 2018 |
| المجموعة: | Repositori Universitat Jaume I (Repositorio UJI) |
| مصطلحات موضوعية: | Management, Osteoporosis, Osteoporosis care, Treatment, Treatment failure, Treat to target, Treat-to-target strategy |
| الوصف: | Summary To reach a Spanish expert consensus on a treat-to-target strategy in osteoporosis, a Delphi Consensus Study has been developed. Most of the experts (59.8%) were rheumatologist with a mean clinical experience of 21.3 years (SD 8.5). Consensus was achieved for 70% of the items. Therapeutic objectives, patient follow-up scheme, treatment failure criteria, and appropriate treatment choice for use in T2T strategy in Spain have been defined. Introduction The paper aims to achieve a Spanish expert consensus on a treat-to-target (T2T) strategy in osteoporosis. Methods A scientific committee led the project and was involved in expert panel identification and Delphi questionnaire development. Two Delphi rounds were completed. The first-round questionnaire included 24 items and assessed, using a seven-point Likert scale, the experts’ wish (W) and prognosis (P) in 5 years for each topic (applicability, therapeutic objectives, patient follow-up, and possible treatment to be prescribed). Items for which there was no consensus in the first round were included in the second round. Consensus was defined as ≥75% agreement (somewhat/mostly/entirely agree) or disagreement (somewhat/mostly/entirely disagree) responses. Results Of the experts, 112 and 106 completed the first and second rounds, respectively. 59.8% were rheumatologists with a mean clinical experience of 21.3 years (SD 8.5). Consensus was achieved for 70% of the items, and was established regarding the utility of a T2T strategy to define therapeutic objectives, optimal follow-up, and therapeutic algorithm. Participants agreed on the utility of the bone mineral density (BMD) value (T-score >−2.5 SD for spine and >−2.5/−2.0 SD for femoral neck), lack of fractures, and fracture risk (FRAX) as therapeutic objectives. For measuring BMD changes, consensus was achieved on the suitability of hip and femoral neck locations. Experts agreed to consider treatment failure as when a significant BMD gain could not be achieved, or when a new fracture occurs within 2–3 ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0937-941X 1433-2965 |
| Relation: | Osteoporos Int (2018) 29; https://link.springer.com/article/10.1007/s00198-017-4310-y; Nogués, X., Nolla, J.M., Casado, E. et al. Osteoporos Int (2018) 29: 489. https://doi.org/10.1007/s00198-017-4310-y; http://hdl.handle.net/10234/174829; https://doi.org/10.1007/s00198-017-4310-y |
| DOI: | 10.1007/s00198-017-4310-y |
| الاتاحة: | http://hdl.handle.net/10234/174829 https://doi.org/10.1007/s00198-017-4310-y |
| Rights: | © The Author(s) 2017 This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. ; Atribución-NoComercial 4.0 Internacional ; http://creativecommons.org/licenses/by-nc/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.7048D276 |
| قاعدة البيانات: | BASE |
| تدمد: | 0937941X 14332965 |
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| DOI: | 10.1007/s00198-017-4310-y |