Academic Journal
Impact of Fatty Pancreas on Postoperative Pancreatic Fistulae: A Meta-Analysis
| العنوان: | Impact of Fatty Pancreas on Postoperative Pancreatic Fistulae: A Meta-Analysis |
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| المؤلفون: | Zhou, Lu, Xiao, Wei-ming, Li, Cheng-peng, Gao, Yi-wen, Gong, Wei-juan, Lu, Guo-tao |
| المصدر: | Frontiers in Oncology ; volume 11 ; ISSN 2234-943X |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2021 |
| المجموعة: | Frontiers (Publisher - via CrossRef) |
| الوصف: | Background Soft pancreas is widely recognized as an important risk factor for the development of postoperative pancreatic fistula (POPF). Although fatty pancreas (FP) has not been formally defined as a cause of pancreatic fistula, existing research has shown that it can increase the incidence of POPF by increasing pancreatic tenderness; therefore, it may be a potential risk factor. This study aimed to discern whether FP was associated with POPF. Method Two reviewers independently performed literature searches from five electronic databases. According to the established inclusion criteria, we extracted necessary data from the studies that met the criteria for further analysis. We pooled the odds ratios (ORs) from individual studies using a random-effects model to investigate the associations between POPF and the prognosis of FP. Result A total of 11 studies involving 2484 individuals were included. The pooled prevalence of POPF was 18% (95% CI: 12-24%). Body mass index (BMI) was associated with a significantly increased risk of POPF (OR=3.55; 95% CI: 1.83, 6.86; P=0.0002; I²=0). FP was obviously associated with the occurrence of POPF (OR=3.75; 95% CI: 1.64, 8.58; P=0.002; I²=78). Conclusion FP is closely associated with the development of POPF, and the early identification of these high-risk patients can help to reduce the incidence of POPF. Systematic Review Registration The Registration URL link is ( https://www.crd.york.ac.uk/PROSPERO/ ). The ID is “CRD42021265141”. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| DOI: | 10.3389/fonc.2021.622282 |
| DOI: | 10.3389/fonc.2021.622282/full |
| الاتاحة: | http://dx.doi.org/10.3389/fonc.2021.622282 https://www.frontiersin.org/articles/10.3389/fonc.2021.622282/full |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.7006CCBD |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fonc.2021.622282 |
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