Academic Journal
Two NRAMP6 isoforms function as Iron and manganese transporters and contribute to disease resistance in rice
| العنوان: | Two NRAMP6 isoforms function as Iron and manganese transporters and contribute to disease resistance in rice |
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| المؤلفون: | Peris-Peris, Cristina, Serra-Cardona, Albert, Sánchez-Sanuy, Ferran, Campo, Sonia, Ariño, Joaquín, San Segundo, Blanca |
| المساهمون: | Ministerio de Economía y Competitividad (España), European Commission, Generalitat de Catalunya |
| بيانات النشر: | American Phytopathological Society |
| سنة النشر: | 2017 |
| المجموعة: | Digital.CSIC (Consejo Superior de Investigaciones Científicas / Spanish National Research Council) |
| الوصف: | Metal ions are essential elements for all living organisms. However, metals can be toxic when present in excess. In plants, metal homeostasis is partly achieved through the function of metal transporters, including the diverse natural resistance-associated macrophage proteins (NRAMP). Among them, the OsNramp6 gene encodes a previously uncharacterized member of the rice NRAMP family that undergoes alternative splicing to produce different NRAMP6 proteins. In this work, we determined the metal transport activity and biological role of the full-length and the shortest NRAMP6 proteins (l-NRAMP6 and s-NRAMP6, respectively). Both l-NRAMP6 and s-NRAMP6 are plasma membrane-localized proteins that function as iron and manganese transporters. The expression of l-Nramp6 and s-Nramp6 is regulated during infection with the fungal pathogen Magnaporthe oryzae, albeit with different kinetics. Rice plants grown under high iron supply show stronger induction of rice defense genes and enhanced resistance to M. oryzae infection. Also, loss of function of OsNramp6 results in enhanced resistance to M. oryzae, supporting the idea that OsNramp6 negatively regulates rice immunity. Furthermore, nramp6 plants showed reduced biomass, pointing to a role of OsNramp6 in plant growth. A better understanding of OsNramp6-mediated mechanisms underlying disease resistance in rice will help in developing appropriate strategies for crop protection. ; This project was funded by the Ministry of Economy and Competitiveness (MINECO) and the European Regional Development’s funds (BIO2012-32838 and BIO2015-67212 to B. San Segundo and BFU2014-54591-C2-1-P to J. Ariño). J. Ariño is recipient of a 2014SGR-4 grant from the Generalitat de Catalunya. We acknowledge the support of the MINECO for the “Centro de Excelencia Severo Ochoa 2016-2019” award SEV-2015-0533. ; Peer reviewed |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0894-0282 |
| Relation: | #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BIO2015-67212-R; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/BFU2014-54591-C2-1-P; info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/SEV-2015-0533; Publisher's version; https://doi.org/10.1094/MPMI-01-17-0005-R; Sí; Molecular Plant-Microbe Interactions 30(5): 385-398 (2017); http://hdl.handle.net/10261/250728; http://dx.doi.org/10.13039/501100002809; http://dx.doi.org/10.13039/501100003329; http://dx.doi.org/10.13039/501100000780 |
| DOI: | 10.1094/MPMI-01-17-0005-R |
| DOI: | 10.13039/501100002809 |
| DOI: | 10.13039/501100003329 |
| DOI: | 10.13039/501100000780 |
| الاتاحة: | http://hdl.handle.net/10261/250728 https://doi.org/10.1094/MPMI-01-17-0005-R https://doi.org/10.13039/501100002809 https://doi.org/10.13039/501100003329 https://doi.org/10.13039/501100000780 |
| Rights: | open |
| رقم الانضمام: | edsbas.6FF26E90 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 08940282 |
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| DOI: | 10.1094/MPMI-01-17-0005-R |