DEVELOPMENT OF NEW CLINICAL DIAGNOSTIC TECHNIQUES IN PROSTHESIS REJECTION CASES BY USING PARTICLE INDUCED X-RAY EMISSION (PIXE)

التفاصيل البيبلوغرافية
العنوان: DEVELOPMENT OF NEW CLINICAL DIAGNOSTIC TECHNIQUES IN PROSTHESIS REJECTION CASES BY USING PARTICLE INDUCED X-RAY EMISSION (PIXE)
المؤلفون: Punzón-Quijorna, Esther, Kelemen, Mitja, Vavpetič, Primož, Fokter, Samo K., Pelicon, Primož
المصدر: ION BEAM ANALYSIS (IBA), Antibes, France, 13-18 October 2019
بيانات النشر: Zenodo
سنة النشر: 2020
المجموعة: Zenodo
مصطلحات موضوعية: TISSUEMAPS, MarieCurie, Diagnostic tools, health care research, tissue imaging, Medical imaging physics, Nuclear microprobes, Biomedical engineering, Health services, endoprosthesis, biocompatible endoprosthesis, Particle Induced X-ray Emission (PIXE), Marie Skłodowska-Curie grant agreement No. 799182
الوصف: Hip prosthesis replacement is one of the most frequent and costly treatments in developed countries. The increased number of patients and the insufficient understanding of physiological processes leading to prosthesis failure make necessary the use of complementary techniques to better understand the degradation of implants [1]. We present two cases of prosthesis failure: Patient 2, with a modular hip prosthesis made of TiAlV alloy (Profemur®), presents a broken neck; and Patient 7, with a Ceramic on Ceramic articulation made of zirconia toughtened alumina (Biolox® Delta), presents a broken acetabular inlay. The presence of metallic debris coming from the prosthesis has been studied by using Particle-Induced X-ray Emission (PIXE). This technique combines high elemental sensitivity (detection limit 0,1 ppm) with high lateral resolution (600 nm) [2]. The analysis was performed with the 2 MV tandem accelerator available at Jožef Stefan Institute (JSI) [3]. [1] Fokter SK, et al., Acta Orthopaedica, 87(2), p.197-202, 2016. [2] P. Vavpetič et al., Nuclear Instruments and Methods in Physics Research B, vol. 306, pp. 140-143, 2013. [3] Primoz Pelicon et al., Nuclear Instruments and Methods in Physics Research B, vol. 332, pp. 229-233, 2014 ; This project, TISSUEMAPS, has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 799182.
نوع الوثيقة: conference object
اللغة: English
Relation: https://doi.org/10.1016/j.nimb.2019.10.019; https://zenodo.org/communities/eu; https://doi.org/10.5281/zenodo.3666263; https://doi.org/10.5281/zenodo.3666264; oai:zenodo.org:3666264
DOI: 10.5281/zenodo.3666264
الاتاحة: https://doi.org/10.5281/zenodo.3666264
Rights: info:eu-repo/semantics/openAccess ; Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode
رقم الانضمام: edsbas.6F9DE418
قاعدة البيانات: BASE