Academic Journal
Inflammatory Biomarkers in Elite Cross-Country Skiers After a Competition Season : A Case-Control Study
| العنوان: | Inflammatory Biomarkers in Elite Cross-Country Skiers After a Competition Season : A Case-Control Study |
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| المؤلفون: | Luoto, Raakel, Ruuskanen, Olli, Ihalainen, Johanna K., Pekkala, Satu, Hintikka, Jukka, Kanerva, Noora, Waris, Matti, Heinonen, Olli J., Valtonen, Maarit |
| المساهمون: | Department of Food and Nutrition |
| بيانات النشر: | Springer Nature |
| سنة النشر: | 2024 |
| المجموعة: | Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto |
| مصطلحات موضوعية: | Athlete, Biomarker, Chronic low-grade inflammation, Exercise, GlycA, Inflammation, Sport and fitness sciences |
| الوصف: | PurposeWhether elite athletes, who have been exposed to vigorous-intensity exercise combined with other stressors, have elevated systemic low-grade inflammation, remains largely unclear. To address this question, we studied the levels of six inflammatory cytokines as potential biomarkers of a low-grade inflammatory state in elite athletes after an 11-month training and competition season.MethodsWe collected sera from 27 Finnish elite cross-country skiers and 27 gender- and age-matched, moderately-exercising controls. The serum concentrations of C-reactive protein (CRP), interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-alpha), glycoprotein acetyls (GlycA), interleukin 10 (IL-10), and interferon gamma (IFN-gamma) cytokines were quantified as surrogate markers of low-grade inflammation.ResultsThe athletes were found to have significantly lower concentrations of CRP (P = 0.0232) and higher concentrations of IL-10, TNF-alpha, and IFN-gamma (P = 0.0097, P = 0.0256, and P = 0.0185, respectively) than the controls. No significant differences between athletes and controls were detected in the concentrations of IL-6 and GlycA. The inflammatory score (IS) did not differ significantly between athletes and controls.ConclusionThe results of this study argued against the hypothesis of a significant chronic low-grade inflammation in response to prolonged high-performance exercise among elite endurance athletes. ; Peer reviewed |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| ردمك: | 978-0-01-098018-9 0-01-098018-0 |
| Relation: | Open Access funding provided by University of Turku (UTU) including University of Turku (UTU). Jenny and Antti Wihuri Foundation; http://hdl.handle.net/10138/570906; 85138288468; 001098018000007 |
| الاتاحة: | http://hdl.handle.net/10138/570906 |
| Rights: | cc_by ; info:eu-repo/semantics/openAccess ; openAccess |
| رقم الانضمام: | edsbas.6EB77EB4 |
| قاعدة البيانات: | BASE |
| ردمك: | 9780010980189 0010980180 |
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