Academic Journal
Long-term cardiovascular outcomes among immigrants and non-immigrants in cardiac resynchronization therapy:a nationwide study
| العنوان: | Long-term cardiovascular outcomes among immigrants and non-immigrants in cardiac resynchronization therapy:a nationwide study |
|---|---|
| المؤلفون: | Krøll, Johanna, Kristensen, Søren Lund, Jespersen, Camilla H B, Philbert, Berit, Vinther, Michael, Risum, Niels, Johansen, Jens Brock, Nielsen, Jens Cosedis, Riahi, Sam, Haarbo, Jens, Fosbøl, Emil L, Torp-Pedersen, Christian, Køber, Lars, Tfelt-Hansen, Jacob, Weeke, Peter E |
| المصدر: | Krøll , J , Kristensen , S L , Jespersen , C H B , Philbert , B , Vinther , M , Risum , N , Johansen , J B , Nielsen , J C , Riahi , S , Haarbo , J , Fosbøl , E L , Torp-Pedersen , C , Køber , L , Tfelt-Hansen , J & Weeke , P E 2023 , ' Long-term cardiovascular outcomes among immigrants and non-immigrants in cardiac resynchronization therapy : a nationwide study ' , Europace , vol. 25 , no. 6 , euad148 . https://doi.org/10.1093/europace/euad148 |
| سنة النشر: | 2023 |
| المجموعة: | Aarhus University: Research |
| مصطلحات موضوعية: | Cardiac Resynchronization Therapy Devices/adverse effects, Cardiac Resynchronization Therapy/methods, Defibrillators, Implantable/adverse effects, Heart Failure/diagnosis, Humans, Proportional Hazards Models, Treatment Outcome, Heart failure, Ethnicity, CRT, Mortality, Epidemiology |
| الوصف: | AIMS: To date, potential differences in outcomes for immigrants and non-immigrants with a cardiac resynchronization therapy (CRT), in a European setting, remain underutilized and unknown. Hence, we examined the efficacy of CRT measured by heart failure (HF)-related hospitalizations and all-cause mortality among immigrants and non-immigrants. METHODS AND RESULTS: All immigrants and non-immigrants who underwent first-time CRT implantation in Denmark (2000-2017) were identified from nationwide registries and followed for up to 5 years. Differences in HF related hospitalizations and all-cause mortality were evaluated by Cox regression analyses. From 2000 to 2017, 369 of 10 741 (3.4%) immigrants compared with 7855 of 223 509 (3.5%) non-immigrants with a HF diagnosis underwent CRT implantation. The origins of the immigrants were Europe (61.2%), Middle East (20.1%), Asia-Pacific (11.9%), Africa (3.5%), and America (3.3%). We found similar high uptake of HF guideline-directed pharmacotherapy before and after CRT and a consistent reduction in HF-related hospitalizations the year before vs. the year after CRT (61% vs. 39% for immigrants and 57% vs. 35% for non-immigrants). No overall difference in 5-year mortality among immigrants and non-immigrants was seen after CRT [24.1% and 25.8%, respectively, P-value = 0.50, hazard ratio (HR) = 1.2, 95% confidence interval (CI): 0.8-1.7]. However, immigrants of Middle Eastern origin had a higher mortality rate (HR = 2.2, 95% CI: 1.2-4.1) compared with non-immigrants. Cardiovascular causes were responsible for the majority of deaths irrespective of immigration status (56.7% and 63.9%, respectively). CONCLUSION: No overall differences in efficacy of CRT in improving outcomes between immigrants and non-immigrants were identified. Although numbers were low, a higher mortality rate among immigrants of Middle Eastern origin was identified compared with non-immigrants. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| DOI: | 10.1093/europace/euad148 |
| الاتاحة: | https://pure.au.dk/portal/en/publications/ef96bd16-ca41-4147-a8d7-5ef6c25710a4 https://doi.org/10.1093/europace/euad148 https://pure.au.dk/ws/files/398437884/euad148.pdf http://www.scopus.com/inward/record.url?scp=85162688339&partnerID=8YFLogxK |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.6CFA9A50 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/europace/euad148 |
|---|