Academic Journal
Muscle Hypertrophy Is Linked to Changes in the Oxidative and Proteolytic Systems during Early Tenderization of the Spanish Breed 'Asturiana de los Valles'
| العنوان: | Muscle Hypertrophy Is Linked to Changes in the Oxidative and Proteolytic Systems during Early Tenderization of the Spanish Breed 'Asturiana de los Valles' |
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| المؤلفون: | García-Macia, Marina, Sierra, Verónica, Santos-Ledo, Adrián, Luxán-Delgado, Beatriz de, Potes-Ochoa, Yaiza, Rodríguez-González, Susana, Oliván, Mamen, Coto-Montes, Ana |
| المساهمون: | CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Universidad de Salamanca, Fundación Eugenio Rodríguez Pascual, European Commission, Consejo Superior de Investigaciones Científicas (España), Junta de Castilla y León, Agencia Estatal de Investigación (España), Ministerio de Ciencia e Innovación (España), Luxán-Delgado, Beatriz de |
| بيانات النشر: | Multidisciplinary Digital Publishing Institute |
| سنة النشر: | 2024 |
| المجموعة: | Digital.CSIC (Consejo Superior de Investigaciones Científicas / Spanish National Research Council) |
| مصطلحات موضوعية: | Asturiana de los Valles, Autophagy, Beef, Lipid oxidation, Meat aging, Muscular hypertrophy, Protein oxidation, Proteolysis, Total antioxidant activity |
| الوصف: | For fresh meat consumers, eating satisfaction is of utmost importance and tenderness is one of the most important characteristics in this regard. Our study examined beef of different animal biotypes of the autochthonous breed "Asturiana de los Valles" (AV) to determine if early postmortem oxidative and proteolytic processes may influence the final tenderness of the product. This meat-specialized breed shows different biotypes depending on the frequency of a myostatin mutation "mh" that induces double-muscling or muscular hypertrophy (mh/mh, mh/+, +/+). Samples from the longissimus dorsi muscles of yearling bulls were analyzed during the first 24 h postmortem. Changes in the redox balance of muscle cells were significant in the first hours after slaughter; total antioxidant activity was higher in the mh/mh biotype and it followed the shortening of the sarcomeres, a key parameter in understanding meat tenderness. The two proteolytic systems studied (proteasome and lysosome) followed distinct patterns. Proteasome activity was higher in the (mh/+) biotype, which correlated with higher protein damage. Lysosome proteolysis was increased in the more tender biotypes (mh genotypes). Autophagic activation showed significant differences between the biotypes, with (mh/mh) showing more intense basal autophagy at the beginning of the postmortem period that decreased gradually (p < 0.001), while in the normal biotype (+/+), it was slightly delayed and then increased progressively (p < 0.001). These results suggest that this type of catalytic process and antioxidant activity could contribute to the earlier disintegration of the myofibers, particularly in the mh/mh biotypes, and influence the conversion of muscle into meat. ; This research was funded by Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA, Spain) under the RTA2007-00087-C02 project; the Universidad de Salamanca: Lanzadera TCUE21-21_003; the Fundación Eugenio Rodríguez Pascual: Convocatoria de ayudas de investigación Biomédica 2021 ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 2304-8158 |
| Relation: | #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MEC//RTA2007-00087-C02-01/ES/Identificación temprana de marcadores proteómicos para optimizar el manejo y la trazabilidad de la carne de vacuno/; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2021-2023/PID2022-138478OA-I00/ES/INDUCIR LIPOFAGIA PARA MEJORAR LA RESPUESTA INMUNITARIA EN LA ESTEATOHEPATITIS ALCOHOLICA (ASH) Y OTRAS ENFERMEDADES METABOLICAS/; info:eu-repo/grantAgreement/AEI//RYC2021-033684-I; https://doi.org/10.3390/foods13030443; Sí; Foods 13(3): 443 (2024); http://hdl.handle.net/10261/362149; 2-s2.0-85184734342; https://api.elsevier.com/content/abstract/scopus_id/85184734342 |
| DOI: | 10.3390/foods13030443 |
| الاتاحة: | http://hdl.handle.net/10261/362149 https://doi.org/10.3390/foods13030443 https://api.elsevier.com/content/abstract/scopus_id/85184734342 |
| Rights: | open |
| رقم الانضمام: | edsbas.6CD7E4CC |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 23048158 |
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| DOI: | 10.3390/foods13030443 |