A second G4 sequence can lead to nascent strand-mediated attenuation of DNA synthesis.

التفاصيل البيبلوغرافية
العنوان: A second G4 sequence can lead to nascent strand-mediated attenuation of DNA synthesis.
المؤلفون: George S. Brush (14304905)
سنة النشر: 2022
مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Evolutionary Biology, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, template strand led, two different effects, rich dna sequence, quadruplex , dna synthesis caused, two effects, rich dna, quadruplex structure, g4 sequence, dna structure, %22">xlink ">, results provide, readout coincident, plasmid vector, novel examples, new example, labeled dideoxynucleotides, internal position, incorrect incorporation
الوصف: (a) Sequence analysis of pG4-2 using the M13F (-47) primer (GENEWIZ). The runs of Cs are indicated with blue lines. (b) Normalized peak heights for DNA sequencing carried out by GENEWIZ (GW) and ( c ) GenScript (GS) are shown for pG4-2 and its mutant derivative, pG4-2-v. Indicated primers were used. For ( b ), the plasmids were sequenced using M13R two times and M13F one time. For ( c ), the plasmids were sequenced four times with M13R, and pG4-2 was sequenced three times and pG4-2-v four times with M13F. Error bars indicate standard deviation.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/A_second_G4_sequence_can_lead_to_nascent_strand-mediated_attenuation_of_DNA_synthesis_/21782957
DOI: 10.1371/journal.pone.0279423.g007
الاتاحة: https://doi.org/10.1371/journal.pone.0279423.g007
Rights: CC BY 4.0
رقم الانضمام: edsbas.6CCDC02A
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pone.0279423.g007