Academic Journal
Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A Narrative Review of Impact and Understanding
| العنوان: | Cancer-Related Genetic Testing and Personalized Medicine for Adolescents: A Narrative Review of Impact and Understanding |
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| المؤلفون: | Vetsch, J, Wakefield, CE, Warby, M, Tucker, K, Patterson, P, McGill, BC, Metcalfe, A, Cohn, RJ, Fardell, JE |
| المصدر: | urn:ISSN:2156-5333 ; urn:ISSN:2156-535X ; Journal of Adolescent and Young Adult Oncology, 7, 3, 259-262 |
| بيانات النشر: | Mary Ann Liebert |
| سنة النشر: | 2018 |
| المجموعة: | UNSW Sydney (The University of New South Wales): UNSWorks |
| مصطلحات موضوعية: | 4203 Health Services and Systems, 32 Biomedical and Clinical Sciences, 42 Health Sciences, 3211 Oncology and Carcinogenesis, Genetics, Clinical Research, Behavioral and Social Science, Prevention, Pediatric, Genetic Testing, Cancer, 7.1 Individual care needs, 6.6 Psychological and behavioural, 3 Good Health and Well Being, Adolescent, Adolescent Behavior, Genetic Counseling, Genetic Predisposition to Disease, Humans, Neoplasms, Precision Medicine, Prognosis, Stress, Psychological, Surveys and Questionnaires, narrative review, oncology, personalized medicine, predictive genetic testing, psychosocial |
| الوصف: | Genetic testing is becoming increasingly available for adolescents who are undergoing cancer treatment or at risk of cancer predisposition syndromes. With this narrative review, we aimed to synthesize the evidence on psychosocial outcomes and adolescents' understanding of genetic testing - thus far, an underresearched topic. Both psychological benefits and harms of predictive testing were reported in adolescents from high-risk families. Harms were mainly related to cancer-specific distress and increased worries. Findings on genetic understanding were sparse. Future studies should focus on psychosocial outcomes and adolescents' understanding undergoing genetic testing and enabling access to genetic counseling pre-testing and post-testing. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| Relation: | http://hdl.handle.net/1959.4/unsworks_54857; https://doi.org/10.1089/jayao.2017.0102 |
| DOI: | 10.1089/jayao.2017.0102 |
| الاتاحة: | http://hdl.handle.net/1959.4/unsworks_54857 https://unsworks.unsw.edu.au/bitstreams/ca3e47ca-e1f1-4580-8560-73aa2de0e9cb/download https://doi.org/10.1089/jayao.2017.0102 |
| Rights: | open access ; https://purl.org/coar/access_right/c_abf2 ; CC-BY-NC-ND ; https://creativecommons.org/licenses/by-nc-nd/4.0/ ; free_to_read |
| رقم الانضمام: | edsbas.6C0A4765 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1089/jayao.2017.0102 |
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