التفاصيل البيبلوغرافية
| العنوان: |
Supramolecular Hydrogel of a D-Amino Acid Dipeptide for Controlled Drug Release in Vivo |
| المؤلفون: |
Liang, Gaolin CHEM, Yang, Zhimou, Zhang, Rongjun, Li, Lihua, Fan, Yijun, Kuang, Yi, Gao, Yuan, Wang, Ting, Lu, W. William, Xu, Bing |
| سنة النشر: |
2009 |
| المجموعة: |
The Hong Kong University of Science and Technology: HKUST Institutional Repository |
| مصطلحات موضوعية: |
Amino Acids: chemistry, Biocompatible Materials: chemistry, Dipeptides: chemistry, Drug Carriers, Drug Delivery Systems, Humans, Hydrogel: chemistry, Hydrogels: chemistry, Iodine Radioisotopes: chemistry, Materials Testing, Microscopy, Electron, Transmission: methods, Models, Chemical, Sodium Iodide: chemistry, Time Factors, Tomography, Emission-Computed, Single-Photon: methods |
| الوصف: |
A supramolecular hydrogel based on D-amino acids, which resists hydrolysis catalyzed by proteinase K and offers long-term biostability, exhibits controlled release in vivo, as proved I-131 the pharmacokinetics of encapsulated I-125 tracers and the SPECT imaging of the hydrogel-encapsulated I tracers. As the first in vivo imaging investigation of the drug release properties of the supramolecular hydrogel, isotope encapsulation serves as a valid, useful assay for characterizing the controlled release properties of supramolecular hydrogels in vivo. Our results indicate that supramolecular hydrogels promise new biomaterials for controlled drug release. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| تدمد: |
0743-7463 |
| Relation: |
http://repository.ust.hk/ir/Record/1783.1-30533; Langmuir, v. 25, (15), August 2009, p. 8419-8422; https://doi.org/10.1021/la804271d; http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0743-7463&rft.volume=25&rft.issue=15&rft.date=2009&rft.spage=8419&rft.aulast=Liang&rft.aufirst=Gaolin&rft.atitle=Supramolecular%20Hydrogel%20of%20a%20D-Amino%20Acid%20Dipeptide%20for%20Controlled%20Drug%20Release%20in%20Vivo&rft.title=; http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000268231500014; http://www.scopus.com/record/display.url?eid=2-s2.0-68149089875&origin=inward |
| DOI: |
10.1021/la804271d |
| الاتاحة: |
http://repository.ust.hk/ir/Record/1783.1-30533
https://doi.org/10.1021/la804271d
http://lbdiscover.ust.hk/uresolver?url_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rfr_id=info:sid/HKUST:SPI&rft.genre=article&rft.issn=0743-7463&rft.volume=25&rft.issue=15&rft.date=2009&rft.spage=8419&rft.aulast=Liang&rft.aufirst=Gaolin&rft.atitle=Supramolecular%20Hydrogel%20of%20a%20D-Amino%20Acid%20Dipeptide%20for%20Controlled%20Drug%20Release%20in%20Vivo&rft.title=
http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=LinksAMR&SrcApp=PARTNER_APP&DestLinkType=FullRecord&DestApp=WOS&KeyUT=000268231500014
http://www.scopus.com/record/display.url?eid=2-s2.0-68149089875&origin=inward |
| رقم الانضمام: |
edsbas.6BC9B30D |
| قاعدة البيانات: |
BASE |