Academic Journal

Cumulative radiation exposure during thoracic endovascular aneurysm repair and subsequent follow-up

التفاصيل البيبلوغرافية
العنوان: Cumulative radiation exposure during thoracic endovascular aneurysm repair and subsequent follow-up
المؤلفون: Zoli, Stefano, Trabattoni, Piero, Dainese, Luca, Annoni, Andrea, Saccu, Claudio, Fumagalli, Miriam, Spirito, Rita, Biglioli, Paolo
بيانات النشر: Oxford University Press
سنة النشر: 2012
المجموعة: HighWire Press (Stanford University)
مصطلحات موضوعية: AORTIC SURGERY
الوصف: OBJECTIVES Thoracic endovascular aneurysm repair (TEVAR) is an appealing alternative to the standard surgical approach, but requires rigorous radiological follow-up. The cumulative radiation exposure (RE) of patients undergoing TEVAR—including pre-operative workup, the procedure and subsequent follow-up computed tomography (CT) imaging—has not previously been investigated. METHODS From August 2003 to February 2011, 48 patients underwent TEVAR at our institution. Mean age was 66 ± 11 years, with 10 patients (21%) aged <60 years. Forty-one (85%) patients were male; 7 (15%) had urgent/emergent operation; 21 (44%) had undergone previous aortic surgery. Mean aortic diameter was 7.3 ± 2.1 cm. Intra-operative screening time and RE were reviewed, and typical institutional thoracic CT scan RE was calculated (17.8 mSv). Life expectancy of an age- and sex-matched population was estimated to assess the cumulative RE from recurrent CT follow-up. RESULTS The average screening time was 15.7 ± 11.4 min, with an RE of 11.3 ± 9 mSv. Obese patients had significantly higher RE during TEVAR (Pearson's coefficient = 0.388, P = 0.019). The RE dropped from 14.9 ± 9.4 mSv to 8.6 ± 7.9 mSv ( P = 0.033) after a hybrid suite was established. Our institutional TEVAR protocol involves one pre-operative thoracoabdominal CT scan and three follow-up thoracic CT scans for the first year, with a yearly evaluation thereafter. The life expectancy of an age- and sex-matched population was 17 years. A patient adhering to our surveillance protocol would be subjected to an overall exposure of 89 mSv at 1 year and 161 mSv at 5 years, with a projected lifetime RE >350 mSv. CONCLUSIONS A 2-year RE exceeding the threshold of 100 mSv with a life expectancy >15 years can be estimated to lead to a lifetime risk increase in radiation-induced leukaemia and solid-tumour cancer >2.7%. The risks of cumulative RE especially in younger and/or obese patients must be balanced with the expected morbidity and mortality reduction in TEVAR versus traditional ...
نوع الوثيقة: text
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اللغة: English
Relation: http://ejcts.oxfordjournals.org/cgi/content/short/42/2/254; http://dx.doi.org/10.1093/ejcts/ezr301
DOI: 10.1093/ejcts/ezr301
الاتاحة: http://ejcts.oxfordjournals.org/cgi/content/short/42/2/254
https://doi.org/10.1093/ejcts/ezr301
Rights: Copyright (C) 2012, European Association for Cardio-Thoracic Surgery
رقم الانضمام: edsbas.6B1A13AA
قاعدة البيانات: BASE