Academic Journal
Fentanyl and Sudden Death—A Postmortem Perspective for Diagnosing and Predicting Risk
| العنوان: | Fentanyl and Sudden Death—A Postmortem Perspective for Diagnosing and Predicting Risk |
|---|---|
| المؤلفون: | Strenja, Ines, Dadić-Hero, Elizabeta, Perković, Manuela, Šoša, Ivan |
| المصدر: | https://www.mdpi.com/2075-4418/14/17/1995 ; Diagnostics ; Volume 14 ; Issue 17 ; ISSN 2075-4418 (Online. |
| سنة النشر: | 2024 |
| المجموعة: | Repository of the University of Rijeka |
| مصطلحات موضوعية: | fentanyl, genetic counseling, hERG, harm reduction, KCNH2 gene, street supply, strip test, overdose, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Sudska medicina, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Forensic Medicine, BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti. Psihijatrija, BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences. Psychiatry |
| الوصف: | Sudden, unexpected deaths are extremely difficult for families, especially when the victim is a child. Most sudden deaths occur due to cardiovascular issues, and a smaller number (approximately one-quarter) are attributed to other causes, such as epilepsy. The medicinal and non-medicinal use of the synthetic opioid fentanyl, which can cause breathing problems, is frequently involved in these deaths. It is also being found more often in autopsies of sudden death cases, and the number of overdose deaths from illicit drugs containing fentanyl is increasing. There are cases in which it is mixed with other drugs. A gene known as the KCNH2 gene or human ether-a-go-go-related gene (hERG), involved in the heart’s electrical activity, can be related to abnormal heart rhythms. This gene, along with others, may play a role in sudden deaths related to fentanyl use. In response, we have examined the scientific literature on genetic variations in the KCNH2 gene that can cause sudden death, the impact of fentanyl on this process, and the potential benefits of genetic testing for the victims to offer genetic counseling for their family members. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | Sveučilište u Rijeci. Medicinski fakultet. Katedra za anatomiju.; University of Rijeka. Faculty of Medicine. Department of Anatomy.; Sveučilište u Rijeci. Medicinski fakultet. Katedra za neurologiju.; University of Rijeka. Faculty of Medicine. Department of Neurology.; Sveučilište u Rijeci. Medicinski fakultet. Katedra za psihijatriju i psihološku medicinu.; University of Rijeka. Faculty of Medicine. Department of Psychiatry and Psychological Medicine.; https://www.unirepository.svkri.uniri.hr/islandora/object/medri:9036; https://urn.nsk.hr/urn:nbn:hr:184:483522; https://www.unirepository.svkri.uniri.hr/islandora/object/medri:9036/datastream/FILE0 |
| الاتاحة: | https://www.unirepository.svkri.uniri.hr/islandora/object/medri:9036 https://urn.nsk.hr/urn:nbn:hr:184:483522 https://www.unirepository.svkri.uniri.hr/islandora/object/medri:9036/datastream/FILE0 |
| Rights: | info:eu-repo/semantics/openAccess ; http://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.6AA563D9 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |