Academic Journal
Insulin Adsorption onto PE and PVC Tubings
| العنوان: | Insulin Adsorption onto PE and PVC Tubings |
|---|---|
| المؤلفون: | Tokhadzé, Nicolas, Sahnoune, Meriem, Devémy, Julien, Dequidt, Alain, Goujon, Florent, Chennell, Philip, Sautou, Valérie, Malfreyt, Patrice |
| المساهمون: | Institut de Chimie de Clermont-Ferrand (ICCF), Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA) |
| المصدر: | ISSN: 2576-6422 ; ACS Applied Bio Materials ; https://hal.science/hal-03682647 ; ACS Applied Bio Materials, 2022, ⟨10.1021/acsabm.2c00029⟩. |
| بيانات النشر: | HAL CCSD ACS Publications |
| سنة النشر: | 2022 |
| المجموعة: | HAL Clermont Auvergne (Université Blaise Pascal Clermont-Ferrand / Université d'Auvergne) |
| مصطلحات موضوعية: | adsorption, insulin, polymeric materials, potential of mean force, microscopic description, plasticized PVC−TOTM surface, HPLC measurements, [PHYS.PHYS.PHYS-CHEM-PH]Physics [physics]/Physics [physics]/Chemical Physics [physics.chem-ph] |
| الوصف: | International audience ; We investigate the adsorption of insulin onto PE and PVC materials by using HPLC measurements and computer simulations. We interpret the experiments by calculating the Gibbs free energy profiles during the adsorption process. The values of free energy of adsorption show a good agreement with the experimental measurements. The adsorption of insulin onto the different materials is characterized through the conformational changes with respect to its conformation in water and the interfacial regions, which are described by specific arrangements of polymer chains, water, insulin, and plasticizer molecules. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-03682647; https://hal.science/hal-03682647; https://hal.science/hal-03682647/document; https://hal.science/hal-03682647/file/pub3-v4.pdf |
| DOI: | 10.1021/acsabm.2c00029 |
| الاتاحة: | https://hal.science/hal-03682647 https://hal.science/hal-03682647/document https://hal.science/hal-03682647/file/pub3-v4.pdf https://doi.org/10.1021/acsabm.2c00029 |
| Rights: | info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.6A4DCE07 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1021/acsabm.2c00029 |
|---|