Academic Journal

Predictive value of CT angiography source image ASPECTS in patients with anterior circulation acute ischemic stroke after endovascular treatment: ultimate infarct size and clinical outcome

التفاصيل البيبلوغرافية
العنوان: Predictive value of CT angiography source image ASPECTS in patients with anterior circulation acute ischemic stroke after endovascular treatment: ultimate infarct size and clinical outcome
المؤلفون: Park, Jung-Soo, Lee, Jong Myong, Kwak, Hyo-Sung, Chung, Gyoung Ho
بيانات النشر: BMJ Publishing Group Ltd
سنة النشر: 2019
المجموعة: HighWire Press (Stanford University)
مصطلحات موضوعية: Ischemic Stroke
الوصف: Background and purpose The objective of this study was to investigate the predictive value of computed tomographic angiography (CTA) source image Alberta Stroke Program Early CT Score (ASPECTS) on clinical outcome and final infarction extent after endovascular treatment (EVT) in patients with acute ischemic stroke (AIS). M ethods All eligible patients from January 2014 to March 2018 undergoing EVT due to anterior circulation AIS were retrospectively reviewed. The baseline ASPECTS on initial noncontrast CT (NCCT) and the CTA source image were compared with the follow-up MR diffusion-weighted imaging (DWI) ASPECTS. Receiver operating characteristic (ROC) curve analysis was used to assess the predictive value of CTA ASPECTS for prediction of final infarct extent and good clinical outcome. Results Our sample included a total of 122 eligible patients (64 males, mean age 70 years) with a median baseline National Institute of Health Stroke Scale (NIHSS) score of 12. Baseline ASPECTS on the CTA source image correlated with follow-up MR DWI ASPECTS better than NCCT ASPECTS (P<0.001). ROC curve analysis revealed baseline CTA ASPECTS (area under the curve [AUC] =0.74, 95% CI: 0.65 to 0.83, P<0.001) can better predict favorable functional outcome than NCCT ASPECTS (AUC=0.64, 95% CI: 0.54 to 0.74, P=0.008). Baseline NIHSS score <15, CTA ASPECTS≥8, and successful recanalization were independent predictors of good clinical outcomes. Conclusion The ASPECTS on the CTA source image provides more information in the prediction of good clinical outcome and final infarction size than NCCT in patients with AIS treated with EVT.
نوع الوثيقة: text
وصف الملف: text/html
اللغة: English
Relation: http://jnis.bmj.com/cgi/content/short/11/4/342; http://dx.doi.org/10.1136/neurintsurg-2018-014359
DOI: 10.1136/neurintsurg-2018-014359
الاتاحة: http://jnis.bmj.com/cgi/content/short/11/4/342
https://doi.org/10.1136/neurintsurg-2018-014359
Rights: Copyright (C) 2019, Society of NeuroInterventional Surgery
رقم الانضمام: edsbas.69B59947
قاعدة البيانات: BASE
الوصف
DOI:10.1136/neurintsurg-2018-014359