Academic Journal

Relation between mixed venous oxygen saturation and cerebral oxygen saturation measured by absolute and relative near-infrared spectroscopy during off-pump coronary artery bypass grafting

التفاصيل البيبلوغرافية
العنوان: Relation between mixed venous oxygen saturation and cerebral oxygen saturation measured by absolute and relative near-infrared spectroscopy during off-pump coronary artery bypass grafting
المؤلفون: Moerman, A., Vandenplas, G., Bové, T., Wouters, P. F., De Hert, S. G.
بيانات النشر: Oxford University Press
سنة النشر: 2013
المجموعة: HighWire Press (Stanford University)
مصطلحات موضوعية: Neurosciences And Neuroanaesthesia
الوصف: Background We hypothesized that previously reported contradictory results regarding the equivalence of mixed venous ( ) and cerebral (rS c O 2 ) oxygen saturation might be related to time delay issues and to measurement technology. In order to explore these two factors, we designed a prospective clinical study comparing with relative (INVOS®) and absolute (Foresight®) rS c O 2 measurements. Methods Forty-two consenting patients undergoing elective off-pump coronary artery bypass grafting were included. Two INVOS and two Foresight sensors continuously registered rS c O 2 . was measured continuously via a pulmonary artery catheter. Data were assessed by within- and between-group comparisons and correlation analysis. Results A similar time delay of 19 (4) and 18 (4) s was found for compared with rS c O 2 measurements by Foresight and INVOS, respectively, during haemodynamic changes. After adjusting for this time delay, the correlation between and rS c O 2 increased from r =0.25 to 0.75 ( P <0.001) for Foresight, and from r =0.28 to 0.73 ( P <0.001) for INVOS. Comparison of Foresight and INVOS revealed significant differences in absolute rS c O 2 values (range 58–89% for Foresight and 28–95% for INVOS). Changes in rS c O 2 in response to acute haemodynamic alterations were significantly more pronounced with INVOS compared with Foresight ( P <0.001). Conclusions Considering the important time delay with , rS c O 2 seems to reflect more appropriately acute haemodynamic alterations. This might suggest its use as a valid alternative to invasive monitoring of tissue oxygen saturation. Relative and absolute rS c O 2 measurements demonstrated significant differences in measured rS c O 2 values and in the magnitude of rS c O 2 changes during haemodynamic alterations.
نوع الوثيقة: text
وصف الملف: text/html
اللغة: English
Relation: http://bja.oxfordjournals.org/cgi/content/short/110/2/258; http://dx.doi.org/10.1093/bja/aes375
DOI: 10.1093/bja/aes375
الاتاحة: http://bja.oxfordjournals.org/cgi/content/short/110/2/258
https://doi.org/10.1093/bja/aes375
Rights: Copyright (C) 2013, Oxford University Press
رقم الانضمام: edsbas.69964AD
قاعدة البيانات: BASE