Academic Journal
Phosphonate Pendant Armed Propylene Cross-Bridged Cyclam: Synthesis and Evaluation as a Chelator for Cu-64
| العنوان: | Phosphonate Pendant Armed Propylene Cross-Bridged Cyclam: Synthesis and Evaluation as a Chelator for Cu-64 |
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| المؤلفون: | Bhatt, Nikunj, Soni, Nisarg, Ha, Yeong Su, Lee, Woonghee, Pandya, Darpan N., Sarkar, Swarbhanu, Kim, Jung Young, Lee, Hochun, Kim, Sun Hee, An, Gwang Il, Yoo, Jeongsoo |
| بيانات النشر: | American Chemical Society |
| سنة النشر: | 2015 |
| المجموعة: | DGIST Scholar (Daegu Gyeongbuk Institute of Science & Technology) |
| مصطلحات موضوعية: | Bifunctional chelator, propylene cross bridge, phosphonate pendant arms, radiopharmaceuticals, ACID, Article, BIOLOGICAL EVALUATION, Chelating Agent, COPPER, Copper 64, Copper Complex, COPPER(II) COMPLEXES, Cyclic Potentiometry, Drug Synthesis, Electron Spin Resonance, emISSION-TOMOGRAPHY, High Performance Liquid Chromatography, INERTNESS, Ion Exchange Chromatography, Ligand, Paraformaldehyde, Phosphonic ACID Derivative, Priority Journal, Propylene, STABILITY |
| الوصف: | A propylene cross-bridged macrocyclic chelator with two phosphonate pendant arms (PCB-TE2P) was synthesized from cyclam. Various properties of the synthesized chelator, including Cu-complexation, Cu-complex stability, 64Cu-radiolabeling, and in vivo behavior, were studied and compared with those of a previously reported propylene cross-bridged chelator (PCB-TE2A). © 2015 American Chemical Society. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| تدمد: | 1948-5875 |
| Relation: | http://hdl.handle.net/20.500.11750/2324; 2-s2.0-84947259180; ACS Medicinal Chemistry Letters, v.6, no.11, pp.1162 - 1166 |
| DOI: | 10.1021/acsmedchemlett.5b00362 |
| الاتاحة: | https://hdl.handle.net/20.500.11750/2324 https://doi.org/10.1021/acsmedchemlett.5b00362 |
| رقم الانضمام: | edsbas.68CC0F82 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 19485875 |
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| DOI: | 10.1021/acsmedchemlett.5b00362 |