Academic Journal
Stability and comparison of complete blood count parameters between capillary and venous blood samples
| العنوان: | Stability and comparison of complete blood count parameters between capillary and venous blood samples |
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| المؤلفون: | Doeleman, Martijn J. H., Esseveld, Anouk, Huisman, Albert, de Roock, Sytze, Tiel Groenestege, Wouter M. |
| المصدر: | International Journal of Laboratory Hematology ; volume 45, issue 5, page 659-667 ; ISSN 1751-5521 1751-553X |
| بيانات النشر: | Wiley |
| سنة النشر: | 2023 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Introduction This study assessed the comparability of complete blood count (CBC) parameters between capillary and venous samples, and extended previous research by examining the influence of different storage temperatures on CBC stability up to 7 days after sample collection. Methods Venous and capillary blood samples were collected from 93 adult patients. Hemoglobin (Hb), hematocrit (Ht), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), mean platelet volume (MPV), leukocytes, lymphocytes, basophils, eosinophils, erythrocytes, red cell distribution width (RDW), immature granulocytes (IG), immature reticulocyte fraction (IRF), monocytes, neutrophils, platelets, and reticulocytes were measured. Deming regression and mean relative differences between venous and capillary measurements were contrasted with desirable total allowable error (TEa). Stability was assessed in 20–27 venous blood samples stored at 4, 21–22, or 30°C, and analyzed at 0, 24, 48, 72, 96, 120, 144, and 168 h. Mean relative change with respect to baseline measurements was compared to the desirable TEa to determine acceptable stability. Results Deming regression demonstrated strong linear correlations and acceptable variation between venous and capillary measurements. Erythrocytes, Hb, Ht, MCH, MCV, RDW, reticulocytes, and platelets showed acceptable stability for at least 96 h at 4°C. Mean relative change exceeded desirable TEa after 24 h at 30°C for all parameters, except erythrocytes, Hb, leukocytes, and MCH. Conclusion Clinical laboratory specialists and clinicians should be aware of potential differences between venous and capillary measurements, and the influence of storage conditions. Clinical validity of delayed CBC analysis depends on the clinical situation and required precision of the result. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/ijlh.14080 |
| الاتاحة: | http://dx.doi.org/10.1111/ijlh.14080 https://onlinelibrary.wiley.com/doi/pdf/10.1111/ijlh.14080 |
| Rights: | http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| رقم الانضمام: | edsbas.6895553B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/ijlh.14080 |
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